8DFG
Crystal structure of potently neutralizing human monoclonal antibody 42D6 Fab in complex with MSP1-19
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | H, I | 42D6 Fab Heavy Chain | polymer | 242 | 26224.3 | 2 | Homo sapiens (Human) | ||
2 | L, M | 42D6 Fab Light Chain | polymer | 217 | 23677.4 | 2 | Homo sapiens (Human) | ||
3 | B, A | Merozoite surface protein 1 | polymer | 105 | 11759.9 | 2 | UniProt (Q8I0U8) Pfam (PF12946) In PDB | Plasmodium falciparum 3D7 | Merozoite surface antigens,PMMSA |
4 | water | water | 18.0 | 341 | Chemie (HOH) |
Sequence modifications
B, A: 1 - 93 (UniProt: Q8I0U8)
PDB | External Database | Details |
---|---|---|
Glu -2 | - | expression tag |
Thr -1 | - | expression tag |
Gly 0 | - | expression tag |
Ala 3 | Ser 1609 | engineered mutation |
Ala 48 | Thr 1654 | engineered mutation |
Gly 94 | - | expression tag |
Thr 95 | - | expression tag |
Lys 96 | - | expression tag |
His 97 | - | expression tag |
His 98 | - | expression tag |
His 99 | - | expression tag |
His 100 | - | expression tag |
His 101 | - | expression tag |
His 102 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 123323.3 | |
All* | Total formula weight | 123323.3 |