Loading
PDBj
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDBDonate
RCSB PDBPDBeBMRBAdv. SearchSearch help

8CI2

human alpha7 nicotinic receptor in complex with the C4 nanobody under sub-saturating conditions

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, E
(A, B, C, D, E)
Neuronal acetylcholine receptor subunit alpha-7polymer38844050.95UniProt (P36544)
Pfam (PF02931)
Pfam (PF02932)
Homo sapiens (human)
2F, G, H
(F, G, I)
Nanobody C4polymer14715826.43Vicugna pacos
3I, J, K, L, M
(P, Q, R, S, T)
2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched424.45In PDB
GlyTouCan (G42666HT)
4N, O, P, Q, R...
(A, B, C, D, E)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.210Chemie (NAG)
Sequence modifications
A, B, C, D, E: 1 - 324 (UniProt: P36544)
A, B, C, D, E: 328 - 375 (UniProt: P36544)
PDBExternal DatabaseDetails
Asp 325-linker
Gly 326-linker
Val 327-linker
Ser 376-expression tag
Ala 377-expression tag
Gly 378-expression tag
Leu 379-expression tag
Thr 380-expression tag
Glu 381-expression tag
Thr 382-expression tag
Ser 383-expression tag
Gln 384-expression tag
Val 385-expression tag
Ala 386-expression tag
Pro 387-expression tag
Ala 388-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight267733.9
BranchedNumber of molecules5
Total formula weight2122.0
Non-Polymers*Number of molecules10
Total formula weight2212.1
All*Total formula weight272068.0
*Water molecules are not included.

238268

PDB entries from 2025-07-02

PDB statisticsPDBj update infoContact PDBjnumon