8CGZ
tubulin-AB8939 complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Tubulin alpha chain | polymer | 451 | 50204.4 | 2 | UniProt (D0VWZ0) Pfam (PF00091) Pfam (PF03953) UniProt (by SIFTS) (A0A836D7T3) | Ovis aries (sheep) | |
| 2 | B, D (B, D) | Tubulin beta chain | polymer | 445 | 49999.9 | 2 | UniProt (D0VWY9) Pfam (PF00091) Pfam (PF03953) | Ovis aries (sheep) | |
| 3 | E (E) | Stathmin-4 | polymer | 143 | 16746.0 | 1 | UniProt (P63043) Pfam (PF00836) | Rattus norvegicus (Norway rat) | Stathmin-like protein B3,RB3 |
| 4 | F, L (A, C) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 2 | Chemie (GTP) | |||
| 5 | G, M (A, C) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 6 | H, N (B, D) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 2 | Chemie (GDP) | |||
| 7 | I, O (B, D) | AB-8939 | non-polymer | 392.5 | 2 | Chemie (UIY) | |||
| 8 | J, K, P (B, D) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 9 | Q, R, S, T, U (A, B, C, D, E) | water | water | 18.0 | 55 | Chemie (HOH) |
Sequence modifications
A, C: 1 - 451 (UniProt: D0VWZ0)
B, D: 1 - 455 (UniProt: D0VWY9)
E: 5 - 145 (UniProt: P63043)
| PDB | External Database | Details |
|---|---|---|
| Ser 232 | Gly 232 | conflict |
| Ser 340 | Thr 340 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Cys 203 | Ser 201 | conflict |
| Ile 318 | Val 316 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Ace 3 | - | acetylation |
| Ala 4 | - | expression tag |
| Ala 14 | Cys 58 | engineered mutation |
| Trp 20 | Phe 64 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 217154.6 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 3054.5 | |
| All* | Total formula weight | 220209.1 |
