8CGV
Tiamulin bound to the 50S subunit
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (0) | Large ribosomal subunit protein bL33 | polymer | 55 | 6388.6 | 1 | UniProt (P0A7N9) Pfam (PF00471) | Escherichia coli BW25113 | 50S ribosomal protein L33 |
| 2 | B (1) | Large ribosomal subunit protein bL34 | polymer | 46 | 5397.5 | 1 | UniProt (P0A7P5) Pfam (PF00468) | Escherichia coli BW25113 | 50S ribosomal protein L34 |
| 3 | C (2) | Large ribosomal subunit protein bL35 | polymer | 65 | 7313.0 | 1 | UniProt (P0A7Q1) Pfam (PF01632) | Escherichia coli BW25113 | 50S ribosomal protein L35,Ribosomal protein A |
| 4 | D (3) | Large ribosomal subunit protein bL36A | polymer | 38 | 4377.4 | 1 | UniProt (P0A7Q6) Pfam (PF00444) | Escherichia coli BW25113 | 50S ribosomal protein L36,Ribosomal protein B |
| 5 | E (a) | 23S rRNA | polymer | 2904 | 941811.6 | 1 | Escherichia coli BW25113 | ||
| 6 | F (b) | 5S rRNA | polymer | 120 | 38790.1 | 1 | Escherichia coli BW25113 | ||
| 7 | G (c) | Large ribosomal subunit protein uL2 | polymer | 273 | 29923.6 | 1 | UniProt (P60422) Pfam (PF00181) Pfam (PF03947) | Escherichia coli BW25113 | 50S ribosomal protein L2 |
| 8 | H (d) | Large ribosomal subunit protein uL3 | polymer | 209 | 22291.6 | 1 | UniProt (P60438) Pfam (PF00297) | Escherichia coli BW25113 | 50S ribosomal protein L3 |
| 9 | I (e) | Large ribosomal subunit protein uL4 | polymer | 201 | 22121.6 | 1 | UniProt (P60723) Pfam (PF00573) | Escherichia coli BW25113 | 50S ribosomal protein L4 |
| 10 | J (g) | Large ribosomal subunit protein uL6 | polymer | 177 | 18932.8 | 1 | UniProt (P0AG55) Pfam (PF00347) | Escherichia coli BW25113 | 50S ribosomal protein L6 |
| 11 | K (h) | Large ribosomal subunit protein bL9 | polymer | 149 | 15789.0 | 1 | UniProt (P0A7R1) Pfam (PF01281) Pfam (PF03948) | Escherichia coli BW25113 | 50S ribosomal protein L9 |
| 12 | L (i) | Large ribosomal subunit protein uL13 | polymer | 142 | 16050.6 | 1 | UniProt (P0AA10) Pfam (PF00572) | Escherichia coli BW25113 | 50S ribosomal protein L13 |
| 13 | M (j) | Large ribosomal subunit protein uL14 | polymer | 123 | 13565.1 | 1 | UniProt (P0ADY3) Pfam (PF00238) | Escherichia coli BW25113 | 50S ribosomal protein L14 |
| 14 | N (k) | 50S ribosomal protein L15 | polymer | 144 | 15008.5 | 1 | UniProt (P02413) Pfam (PF00828) | Escherichia coli BW25113 | Large ribosomal subunit protein uL15 |
| 15 | O (l) | Large ribosomal subunit protein uL16 | polymer | 136 | 15329.3 | 1 | UniProt (P0ADY7) Pfam (PF00252) | Escherichia coli BW25113 | 50S ribosomal protein L16 |
| 16 | P (m) | Large ribosomal subunit protein bL17 | polymer | 127 | 14393.7 | 1 | UniProt (P0AG44) Pfam (PF01196) | Escherichia coli BW25113 | 50S ribosomal protein L17 |
| 17 | Q (n) | Large ribosomal subunit protein uL18 | polymer | 117 | 12794.7 | 1 | UniProt (P0C018) Pfam (PF00861) | Escherichia coli BW25113 | 50S ribosomal protein L18 |
| 18 | R (o) | Large ribosomal subunit protein bL19 | polymer | 115 | 13159.3 | 1 | UniProt (P0A7K6) Pfam (PF01245) | Escherichia coli BW25113 | 50S ribosomal protein L19 |
| 19 | S (p) | Large ribosomal subunit protein bL20 | polymer | 118 | 13528.0 | 1 | UniProt (P0A7L3) Pfam (PF00453) | Escherichia coli BW25113 | 50S ribosomal protein L20 |
| 20 | T (q) | Large ribosomal subunit protein bL21 | polymer | 103 | 11586.4 | 1 | UniProt (P0AG48) Pfam (PF00829) | Escherichia coli BW25113 | 50S ribosomal protein L21 |
| 21 | U (r) | Large ribosomal subunit protein uL22 | polymer | 110 | 12253.4 | 1 | UniProt (P61175) Pfam (PF00237) | Escherichia coli BW25113 | 50S ribosomal protein L22 |
| 22 | V (s) | Large ribosomal subunit protein uL23 | polymer | 100 | 11222.2 | 1 | UniProt (P0ADZ0) Pfam (PF00276) | Escherichia coli BW25113 | 50S ribosomal protein L23 |
| 23 | W (t) | Large ribosomal subunit protein uL24 | polymer | 104 | 11339.3 | 1 | UniProt (P60624) Pfam (PF00467) Pfam (PF17136) | Escherichia coli BW25113 | 50S ribosomal protein L24 |
| 24 | X (u) | 50S ribosomal protein L25 | polymer | 94 | 10713.5 | 1 | UniProt (P68919) Pfam (PF01386) | Escherichia coli BW25113 | Large ribosomal subunit protein bL25 |
| 25 | Y (v) | Large ribosomal subunit protein bL27 | polymer | 85 | 9146.5 | 1 | UniProt (P0A7L8) Pfam (PF01016) | Escherichia coli BW25113 | 50S ribosomal protein L27 |
| 26 | Z (w) | Large ribosomal subunit protein bL28 | polymer | 78 | 9027.6 | 1 | UniProt (P0A7M2) Pfam (PF00830) | Escherichia coli BW25113 | 50S ribosomal protein L28 |
| 27 | AA (x) | Large ribosomal subunit protein uL29 | polymer | 63 | 7286.5 | 1 | UniProt (P0A7M6) Pfam (PF00831) | Escherichia coli BW25113 | 50S ribosomal protein L29 |
| 28 | BA (y) | Large ribosomal subunit protein uL30 | polymer | 59 | 6554.8 | 1 | UniProt (P0AG51) Pfam (PF00327) | Escherichia coli BW25113 | 50S ribosomal protein L30 |
| 29 | CA (z) | Large ribosomal subunit protein bL32 | polymer | 57 | 6463.4 | 1 | UniProt (P0A7N4) Pfam (PF01783) | Escherichia coli BW25113 | 50S ribosomal protein L32 |
| 30 | DA (3) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 31 | EA, FA (a) | Pentacycline | non-polymer | 551.6 | 2 | Chemie (P8F) | |||
| 32 | GA (a) | TIAMULIN | non-polymer | 493.7 | 1 | Chemie (MUL) | |||
| 33 | AB, AC, AD, AE, AF... (a, b, c, d, p...) | MAGNESIUM ION | non-polymer | 24.3 | 219 | Chemie (MG) | |||
| 34 | AI, AJ, AK, BI, BJ... (a, c, e, t, v) | POTASSIUM ION | non-polymer | 39.1 | 83 | Chemie (K) | |||
| 35 | AM, BM, CM, DM, EM... (3, a, b, c, d...) | water | water | 18.0 | 6570 | Chemie (HOH) |
Sequence modifications
l: 1 - 136 (UniProt: P0ADY7)
| PDB | External Database | Details |
|---|---|---|
| Ms6 82 | Met 82 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 29 |
| Total formula weight | 1322559.3 | |
| Non-Polymers* | Number of molecules | 306 |
| Total formula weight | 10230.2 | |
| All* | Total formula weight | 1332789.5 |
