8CES
Crystal structure of monkeypox virus methyltransferase VP39 in complex with inhibitor TO500
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase | polymer | 307 | 35949.5 | 2 | UniProt (A0A0F6N8X1) Pfam (PF01358) UniProt (by SIFTS) (A0A7H0DN74) | Monkeypox virus | |
| 2 | C, D (A, B) | (2~{S})-2-azanyl-4-[[(2~{S},3~{S},4~{R},5~{R})-5-[4-azanyl-5-[2-(1~{H}-benzimidazol-2-yl)ethynyl]pyrrolo[2,3-d]pyrimidin-7-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methylsulfanyl]butanoic acid | non-polymer | 523.6 | 2 | Chemie (UH2) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 42 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 71899.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1047.1 | |
| All* | Total formula weight | 72946.1 |
