8CAA
Crystal structure of TEAD4 in complex with YTP-13
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Transcriptional enhancer factor TEF-3 | polymer | 220 | 25597.8 | 2 | UniProt (Q15561) Pfam (PF17725) In PDB | Homo sapiens (human) | TEA domain family member 4,TEAD-4,Transcription factor 13-like 1,Transcription factor RTEF-1 |
| 2 | A, B | 4-[bis(fluoranyl)methoxy]-2-[(2~{S})-5-chloranyl-6-fluoranyl-2-[[(4-oxidanylcyclohexyl)amino]methyl]-2-phenyl-3~{H}-1-benzofuran-4-yl]-3-fluoranyl-benzamide | non-polymer | 579.0 | 2 | Chemie (U3F) | |||
| 3 | A, B | (2~{R})-2-[2-chloranyl-5-[2-chloranyl-4-(trifluoromethyl)phenoxy]phenyl]sulfanylpropanoic acid | non-polymer | 411.2 | 2 | Chemie (U3O) | |||
| 4 | B | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 5 | water | water | 18.0 | 166 | Chemie (HOH) |
Sequence modifications
A, B: 217 - 434 (UniProt: Q15561)
| PDB | External Database | Details |
|---|---|---|
| Gly 215 | - | expression tag |
| Pro 216 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 51195.7 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 2075.4 | |
| All* | Total formula weight | 53271.1 |
