Loading
PDBj
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDBDonate
RCSB PDBPDBeBMRBAdv. SearchSearch help

8C3U

Crystal Structure of human IL-1beta in complex with a low molecular weight antagonist

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Interleukin-1 betapolymer15317395.82UniProt (P01584)
Pfam (PF00340)
Homo sapiens (human)IL-1 beta,Catabolin
2C, D
(A, B)
(S)-4'-hydroxy-3'-(6-methyl-2-oxo-3-(1H-pyrazol-4-yl)indolin-3-yl)-[1,1'-biphenyl]-2,4-dicarboxylic acidnon-polymer469.42Chemie (T9C)
3E, F
(A, B)
waterwater18.0202Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight34791.7
Non-Polymers*Number of molecules2
Total formula weight938.9
All*Total formula weight35730.6
*Water molecules are not included.

237735

PDB entries from 2025-06-18

PDB statisticsPDBj update infoContact PDBjnumon