8C07
Structure of HECT E3 UBR5 forming K48 linked Ubiquitin chains
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (B, J) | E3 ubiquitin-protein ligase UBR5 | polymer | 2806 | 310266.2 | 2 | UniProt (O95071) Pfam (PF11547) Pfam (PF00658) Pfam (PF00632) | Homo sapiens (human) | E3 ubiquitin-protein ligase,HECT domain-containing 1,HECT-type E3 ubiquitin transferase UBR5,Hyperplastic discs protein homolog,hHYD,Progestin-induced protein |
| 2 | B (I) | Polyubiquitin-B | polymer | 76 | 8550.8 | 1 | UniProt (P0CG47) Pfam (PF00240) | Homo sapiens (human) | |
| 3 | C (K) | Polyubiquitin-B | polymer | 76 | 8576.8 | 1 | UniProt (P0CG47) Pfam (PF00240) | Homo sapiens (human) | |
| 4 | E (K) | 5-azanylpentan-2-one | non-polymer | 101.1 | 1 | Chemie (SY8) |
Sequence modifications
B, J: 1 - 2799 (UniProt: O95071)
I: 1 - 76 (UniProt: P0CG47)
| PDB | External Database | Details |
|---|---|---|
| Gly -6 | - | expression tag |
| Ser -5 | - | expression tag |
| Gly -4 | - | expression tag |
| Ser -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Ala -1 | - | expression tag |
| Pro 0 | - | expression tag |
| Arg 503 | Lys 503 | engineered mutation |
| Asp 710 | Leu 710 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Cys 48 | Lys 48 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 637660.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 101.1 | |
| All* | Total formula weight | 637761.1 |
