8BX2

Oct4/Sox2 protein:DNA complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	E	Transcription factor SOX-2	polymer	83	10092.9	1	UniProt (P48432) Pfam (PF00505) In PDB	Mus musculus (house mouse)
2	A	POU domain, class 5, transcription factor 1	polymer	155	17962.9	1	UniProt (P20263) Pfam (PF00157) Pfam (PF00046) In PDB	Mus musculus (house mouse)	NF-A3,Octamer-binding protein 3,Oct-3,Octamer-binding protein 4,Oct-4,Octamer-binding transcription factor 3,OTF-3
3	C	UTF1_r	polymer	22	6781.4	1		Mus musculus (house mouse)
4	D	UTF1_f	polymer	22	6719.4	1		Mus musculus (house mouse)

Sequence modifications

E: 1 - 80 (UniProt: P48432)

PDB	External Database	Details
Gly -2	-	expression tag
Ala -1	-	expression tag
Met 0	-	expression tag

A: 1 - 152 (UniProt: P20263)

PDB	External Database	Details
Gly -2	-	expression tag
Ala -1	-	expression tag
Met 0	-	expression tag
Ser 48	Cys 178	conflict
Ser 61	Cys 191	conflict
Ser 84	Cys 214	conflict
Ser 115	Cys 245	conflict
Ser 142	Cys 272	conflict

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	41556.5
All*	Total formula weight	41556.5

*Water molecules are not included.