8BFF
Human PPARgamma in complex with MINCH bound to the AF-2 sub-pocket
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Peroxisome proliferator-activated receptor gamma | polymer | 283 | 32412.6 | 3 | UniProt (P37231) Pfam (PF00104) | Homo sapiens (human) | PPAR-gamma,Nuclear receptor subfamily 1 group C member 3 |
| 2 | D (A) | (1~{S},2~{R})-2-[(4~{R})-4-methylheptoxy]carbonylcyclohexane-1-carboxylic acid | non-polymer | 284.4 | 1 | Chemie (QG6) | |||
| 3 | E, F, G (A, B, C) | water | water | 18.0 | 12 | Chemie (HOH) |
Sequence modifications
A, B, C: 206 - 477 (UniProt: P37231)
| PDB | External Database | Details |
|---|---|---|
| Met 195 | - | initiating methionine |
| Arg 196 | - | expression tag |
| Gly 197 | - | expression tag |
| Ser 198 | - | expression tag |
| His 199 | - | expression tag |
| His 200 | - | expression tag |
| His 201 | - | expression tag |
| His 202 | - | expression tag |
| His 203 | - | expression tag |
| His 204 | - | expression tag |
| Gly 205 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 97237.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 284.4 | |
| All* | Total formula weight | 97522.1 |
