8BFF

Human PPARgamma in complex with MINCH bound to the AF-2 sub-pocket

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C	Peroxisome proliferator-activated receptor gamma	polymer	283	32412.6	3	UniProt (P37231) Pfam (PF00104) In PDB	Homo sapiens (human)	PPAR-gamma,Nuclear receptor subfamily 1 group C member 3
2	A	(1~{S},2~{R})-2-[(4~{R})-4-methylheptoxy]carbonylcyclohexane-1-carboxylic acid	non-polymer		284.4	1	Chemie (QG6)
3		water	water		18.0	12	Chemie (HOH)

Sequence modifications

A, B, C: 206 - 477 (UniProt: P37231)

PDB	External Database	Details
Met 195	-	initiating methionine
Arg 196	-	expression tag
Gly 197	-	expression tag
Ser 198	-	expression tag
His 199	-	expression tag
His 200	-	expression tag
His 201	-	expression tag
His 202	-	expression tag
His 203	-	expression tag
His 204	-	expression tag
Gly 205	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	97237.7
Non-Polymers*	Number of molecules	1
	Total formula weight	284.4
All*	Total formula weight	97522.1

*Water molecules are not included.