8BFF
Human PPARgamma in complex with MINCH bound to the AF-2 sub-pocket
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003677 | molecular_function | DNA binding |
A | 0004879 | molecular_function | nuclear receptor activity |
A | 0005634 | cellular_component | nucleus |
A | 0006355 | biological_process | regulation of DNA-templated transcription |
B | 0003677 | molecular_function | DNA binding |
B | 0004879 | molecular_function | nuclear receptor activity |
B | 0005634 | cellular_component | nucleus |
B | 0006355 | biological_process | regulation of DNA-templated transcription |
C | 0003677 | molecular_function | DNA binding |
C | 0004879 | molecular_function | nuclear receptor activity |
C | 0005634 | cellular_component | nucleus |
C | 0006355 | biological_process | regulation of DNA-templated transcription |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 12 |
Details | BINDING: BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG |
Chain | Residue | Details |
A | GLN286 | |
C | HIS323 | |
C | HIS449 | |
C | TYR473 | |
A | HIS323 | |
A | HIS449 | |
A | TYR473 | |
B | GLN286 | |
B | HIS323 | |
B | HIS449 | |
B | TYR473 | |
C | GLN286 |
site_id | SWS_FT_FI2 |
Number of Residues | 6 |
Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:36737649 |
Chain | Residue | Details |
A | LYS224 | |
B | LYS224 | |
C | LYS224 |