8A64
cryoEM structure of the catalytically inactive EndoS from S. pyogenes in complex with the Fc region of immunoglobulin G1.
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Endo-beta-N-acetylglucosaminidase F2 | polymer | 960 | 108297.0 | 1 | UniProt (J7M8R4) Pfam (PF20746) Pfam (PF22382) UniProt (by SIFTS) (Q99Y92) In PDB | Streptococcus pyogenes | |
| 2 | B, C | Immunoglobulin gamma-1 heavy chain | polymer | 449 | 49386.6 | 2 | Pfam (PF07686) Pfam (PF07654) UniProt (by SIFTS) (P0DOX5) In PDB | Homo sapiens (human) | |
| 3 | D | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) |
Sequence modifications
A: 37 - 995 (UniProt: J7M8R4)
| PDB | External Database | Details |
|---|---|---|
| Ala 235 | Glu 253 | engineered mutation |
| Leu 996 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 207070.3 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 586.5 | |
| All* | Total formula weight | 207656.9 |
