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8A11

Cryo-EM structure of the Human SHMT1-RNA complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Serine hydroxymethyltransferase, cytosolicpolymer48653434.84UniProt (P34896)
Pfam (PF00464)
Homo sapiens (human)SHMT,Glycine hydroxymethyltransferase,Serine methylase
2E, F, G
(A, C, D)
PYRIDOXAL-5'-PHOSPHATEnon-polymer247.13Chemie (PLP)
Sequence modifications
A, B, C, D: 1 - 483 (UniProt: P34896)
PDBExternal DatabaseDetails
Gly -2-expression tag
Ser -1-expression tag
His 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight213739.2
Non-Polymers*Number of molecules3
Total formula weight741.4
All*Total formula weight214480.6
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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