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8A11

Cryo-EM structure of the Human SHMT1-RNA complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, DSerine hydroxymethyltransferase, cytosolicpolymer48653434.84UniProt (P34896)
Pfam (PF00464)
In PDB
Homo sapiens (human)SHMT,Glycine hydroxymethyltransferase,Serine methylase
2A, C, DPYRIDOXAL-5'-PHOSPHATEnon-polymer247.13Chemie (PLP)
Sequence modifications
A, B, C, D: 1 - 483 (UniProt: P34896)
PDBExternal DatabaseDetails
Gly -2-expression tag
Ser -1-expression tag
His 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight213739.2
Non-Polymers*Number of molecules3
Total formula weight741.4
All*Total formula weight214480.6
*Water molecules are not included.

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PDB entries from 2024-10-16

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