7ZYI
Structure of the human sodium/bile acid cotransporter (NTCP) in complex with Fab and nanobody
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Sodium/bile acid cotransporter | polymer | 349 | 38149.9 | 1 | UniProt (Q14973) Pfam (PF01758) | Homo sapiens (human) | Cell growth-inhibiting gene 29 protein,Na(+)/bile acid cotransporter,Na(+)/taurocholate transport protein,Sodium/taurocholate cotransporting polypeptide,Solute carrier family 10 member 1 |
| 2 | B (H) | heavy chain of Fab | polymer | 238 | 25582.5 | 1 | Mus musculus | ||
| 3 | C (L) | light chain of Fab | polymer | 215 | 23418.0 | 1 | Mus musculus | ||
| 4 | D (K) | Nanobody | polymer | 120 | 13118.4 | 1 | Lama glama | ||
| 5 | E, H (A) | CHOLESTEROL | non-polymer | 386.7 | 2 | Chemie (CLR) PubChem (304) PubChem (191463) PubChem (368063) PubChem (369319) PubChem (638019) PubChem (1549081) PubChem (1553803) PubChem (5283629) PubChem (5284644) PubChem (5315842) PubChem (6419195) PubChem (6994560) PubChem (7055705) PubChem (7055706) PubChem (7059398) PubChem (7059400) PubChem (7059635) PubChem (7103033) PubChem (7182477) PubChem (7182478) PubChem (9909206) PubChem (10045721) PubChem (71168115) PubChem (10134774) PubChem (10293553) PubChem (71173031) PubChem (11003580) PubChem (11025495) PubChem (11058155) PubChem (11463329) PubChem (11868624) PubChem (11868625) PubChem (11869366) PubChem (11869367) PubChem (11869368) PubChem (11869369) PubChem (12120344) PubChem (12156156) PubChem (12303135) PubChem (12303148) PubChem (12303156) PubChem (12303159) PubChem (12303160) PubChem (16219173) PubChem (16758052) PubChem (40477506) PubChem (40557614) PubChem (42579431) PubChem (42579432) PubChem (176980071) PubChem (45044259) PubChem (18640088) PubChem (1715243) PubChem (1715244) PubChem (23423981) PubChem (49853509) PubChem (44654663) PubChem (46937002) PubChem (59274407) PubChem (50990013) PubChem (68311425) PubChem (68311398) PubChem (143173313) PubChem (177156123) PubChem (5997) PubChem (1551269) PubChem (90070115) PubChem (52934537) PubChem (117965027) PubChem (6432564) PubChem (6710666) PubChem (124146240) PubChem (56621683) PubChem (7059399) PubChem (124897607) PubChem (124896959) PubChem (10861996) PubChem (132837164) PubChem (11834483) PubChem (11888915) PubChem (11888914) PubChem (57915018) PubChem (57939063) PubChem (138967089) PubChem (58428240) PubChem (58445498) PubChem (139566851) PubChem (58663286) PubChem (15939944) PubChem (59450329) PubChem (59628412) PubChem (171828367) PubChem (173516975) PubChem (59965215) PubChem (71234641) PubChem (59993755) PubChem (60001463) PubChem (66634651) PubChem (68055877) PubChem (68166463) PubChem (68315613) PubChem (70795838) PubChem (70797612) PubChem (70954610) PubChem (70957185) PubChem (71463909) PubChem (89951918) PubChem (90224410) PubChem (91298236) PubChem (101624109) PubChem (124225449) PubChem (124429284) PubChem (124909223) PubChem (124909224) PubChem (124909225) PubChem (130459183) PubChem (131992107) PubChem (139568882) PubChem (142983773) PubChem (144054483) PubChem (144209461) PubChem (144331236) PubChem (144808354) PubChem (145053568) PubChem (145157652) PubChem (145215073) PubChem (145230478) PubChem (146320991) PubChem (147857230) PubChem (154993519) PubChem (158603858) PubChem (162906452) PubChem (162906453) PubChem (162906454) PubChem (162906455) PubChem (162906456) PubChem (162906457) PubChem (163255768) PubChem (163389210) PubChem (164665303) PubChem (166553771) PubChem (166712004) PubChem (170116175) PubChem (171764280) PubChem (171817101) PubChem (171817104) PubChem (174285573) | |||
| 6 | F, G (A) | GLYCOCHENODEOXYCHOLIC ACID | non-polymer | 449.6 | 2 | Chemie (CHO) PubChem (93353) PubChem (440686) PubChem (10095257) PubChem (10389035) PubChem (10994028) PubChem (12310284) PubChem (12310285) PubChem (12310287) PubChem (12310288) PubChem (17753896) PubChem (22808456) PubChem (22833540) PubChem (44312819) PubChem (45052109) PubChem (46839357) PubChem (16213700) PubChem (22808055) PubChem (53477907) PubChem (49874127) PubChem (12544) PubChem (27929) PubChem (86312246) PubChem (86331068) PubChem (86310766) PubChem (90474429) PubChem (91746178) PubChem (91798922) PubChem (92450270) PubChem (97629473) PubChem (53391261) PubChem (99564957) PubChem (56606329) PubChem (124335016) PubChem (124784355) PubChem (124899320) PubChem (9933432) PubChem (134692575) PubChem (134555903) PubChem (57696971) PubChem (12310291) PubChem (12310290) PubChem (58104997) PubChem (70420975) PubChem (76329458) PubChem (86310768) PubChem (86312248) PubChem (86328252) PubChem (86331070) PubChem (94029808) PubChem (99564958) PubChem (99564959) PubChem (99566017) PubChem (118554507) PubChem (122361926) PubChem (124350391) PubChem (124350392) PubChem (124422684) PubChem (124899321) PubChem (124899323) PubChem (124902784) PubChem (124902786) PubChem (124902792) PubChem (124905412) PubChem (126963422) PubChem (126968461) PubChem (129317599) PubChem (131632351) PubChem (133109218) PubChem (133612048) PubChem (133688432) PubChem (137349097) PubChem (139024238) PubChem (139291853) PubChem (139291854) PubChem (142492682) PubChem (159623905) PubChem (163025202) PubChem (163198935) PubChem (163337735) PubChem (175271619) | |||
| 7 | I, J (A) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) PubChem (923) | |||
| 8 | K (A) | water | water | 18.0 | 1 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 100268.8 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1718.5 | |
| All* | Total formula weight | 101987.4 |
