7ZSQ
human purine nucleoside phosphorylase in complex with JS-555
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C | Purine nucleoside phosphorylase | polymer | 269 | 27724.6 | 3 | UniProt (A0A045IAS2) Pfam (PF01048) UniProt (by SIFTS) (P9WP01) In PDB | Mycobacterium tuberculosis | Inosine-guanosine phosphorylase |
| 2 | A, B, C | [2-[(4-oxidanylidene-3,5-dihydropyrrolo[3,2-d]pyrimidin-7-yl)sulfanyl]phenoxy]methylphosphonic acid | non-polymer | 353.3 | 3 | Chemie (JTO) | |||
| 3 | A | 6-tungstotellurate(VI) | non-polymer | 1614.6 | 1 | Chemie (TEW) | |||
| 4 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | B | polyethylene glycol | non-polymer | 662.8 | 1 | Chemie (P4K) | |||
| 6 | B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 7 | C | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 8 | water | water | 18.0 | 417 | Chemie (HOH) |
Sequence modifications
A, B, C: 2 - 268 (UniProt: A0A045IAS2)
| PDB | External Database | Details |
|---|---|---|
| Val 1 | - | expression tag |
| Arg 269 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 83173.8 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 3597.6 | |
| All* | Total formula weight | 86771.3 |
