7ZSC

Crystal structure of the heterodimeric human C-P4H-II with truncated alpha subunit (C-P4H-II delta281)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Prolyl 4-hydroxylase subunit alpha-2	polymer	262	30290.2	2	UniProt (O15460) Pfam (PF13640) In PDB	Homo sapiens (human)	4-PH alpha-2,Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-2
2	C, D	Protein disulfide-isomerase	polymer	492	55496.0	2	UniProt (P07237) Pfam (PF00085) Pfam (PF13848) In PDB	Homo sapiens (human)	PDI,Cellular thyroid hormone-binding protein,Prolyl 4-hydroxylase subunit beta,p55
3	A, B	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)

Sequence modifications

A, B: 282 - 535 (UniProt: O15460)

PDB	External Database	Details
Met 274	-	initiating methionine
His 275	-	expression tag
His 276	-	expression tag
His 277	-	expression tag
His 278	-	expression tag
His 279	-	expression tag
His 280	-	expression tag
Met 281	-	expression tag

C, D: 18 - 508 (UniProt: P07237)

PDB	External Database	Details
Met 17	-	initiating methionine

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	171572.4
Non-Polymers*	Number of molecules	2
	Total formula weight	192.1
All*	Total formula weight	171764.5

*Water molecules are not included.