7ZNJ
Structure of an ALYREF-exon junction complex hexamer
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, a, F, f, K... | Eukaryotic initiation factor 4A-III, N-terminally processed | polymer | 382 | 43819.4 | 6 | UniProt (P38919) Pfam (PF00270) Pfam (PF00271) In PDB | Homo sapiens (human) | |
2 | B, b, G, g, L... | Protein mago nashi homolog | polymer | 146 | 17189.6 | 6 | UniProt (P61326) Pfam (PF02792) In PDB | Homo sapiens (human) | |
3 | C, c, H, h, M... | RNA-binding protein 8A | polymer | 91 | 10370.5 | 6 | UniProt (Q9Y5S9) Pfam (PF00076) In PDB | Homo sapiens (human) | Binder of OVCA1-1,BOV-1,RNA-binding motif protein 8A,RNA-binding protein Y14,Ribonucleoprotein RBM8A |
4 | D, d, I, i, N... | Maltose/maltodextrin-binding periplasmic protein,THO complex subunit 4 | polymer | 527 | 57598.9 | 6 | UniProt (P0AEY0) UniProt (Q86V81) Pfam (PF01547) Pfam (PF00076) In PDB | Homo sapiens (human) | MMBP,Maltodextrin-binding protein,Maltose-binding protein,MBP,Tho4,Ally of AML-1 and LEF-1,Aly/REF export factor,Transcriptional coactivator Aly/REF,bZIP-enhancing factor BEF |
5 | E, e, J, j, O... | RNA | polymer | 6 | 1792.0 | 6 | Homo sapiens | ||
6 | A, a, F, f, K... | MAGNESIUM ION | non-polymer | 24.3 | 6 | Chemie (MG) | |||
7 | A, a, F, f, K... | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 6 | Chemie (ANP) |
Sequence modifications
D, d, I, i, N, n: -330 - 39 (UniProt: P0AEY0)
D, d, I, i, N, n: 56 - 182 (UniProt: Q86V81)
PDB | External Database | Details |
---|---|---|
Met -344 | - | initiating methionine |
Gln -343 | - | expression tag |
Leu -342 | - | expression tag |
Ser -341 | - | expression tag |
His -340 | - | expression tag |
His -339 | - | expression tag |
His -338 | - | expression tag |
His -337 | - | expression tag |
His -336 | - | expression tag |
His -335 | - | expression tag |
His -334 | - | expression tag |
His -333 | - | expression tag |
His -332 | - | expression tag |
His -331 | - | expression tag |
Ser -329 | Ala 24 | conflict |
Gly -328 | Leu 25 | conflict |
Met -327 | Ala 26 | conflict |
Ser 40 | - | linker |
Ser 41 | - | linker |
Gly 42 | - | linker |
Leu 43 | - | linker |
Glu 44 | - | linker |
Val 45 | - | linker |
Leu 46 | - | linker |
Phe 47 | - | linker |
Gln 48 | - | linker |
Gly 49 | - | linker |
Pro 50 | - | linker |
Gly 51 | - | linker |
Ser 52 | - | linker |
Ser 53 | - | linker |
Gly 54 | - | linker |
Ile 55 | - | linker |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 30 |
Total formula weight | 784622.5 | |
Non-Polymers* | Number of molecules | 12 |
Total formula weight | 3183.0 | |
All* | Total formula weight | 787805.5 |