7ZNJ

Structure of an ALYREF-exon junction complex hexamer

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0000184	biological_process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
A	0000398	biological_process	mRNA splicing, via spliceosome
A	0003676	molecular_function	nucleic acid binding
A	0003723	molecular_function	RNA binding
A	0003724	molecular_function	RNA helicase activity
A	0003729	molecular_function	mRNA binding
A	0004386	molecular_function	helicase activity
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005681	cellular_component	spliceosomal complex
A	0005730	cellular_component	nucleolus
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006364	biological_process	rRNA processing
A	0006397	biological_process	mRNA processing
A	0006406	biological_process	mRNA export from nucleus
A	0006417	biological_process	regulation of translation
A	0008143	molecular_function	poly(A) binding
A	0008306	biological_process	associative learning
A	0008380	biological_process	RNA splicing
A	0010629	biological_process	negative regulation of gene expression
A	0016020	cellular_component	membrane
A	0016071	biological_process	mRNA metabolic process
A	0016607	cellular_component	nuclear speck
A	0016787	molecular_function	hydrolase activity
A	0016887	molecular_function	ATP hydrolysis activity
A	0017148	biological_process	negative regulation of translation
A	0030425	cellular_component	dendrite
A	0035145	cellular_component	exon-exon junction complex
A	0035368	molecular_function	selenocysteine insertion sequence binding
A	0035613	molecular_function	RNA stem-loop binding
A	0035640	biological_process	exploration behavior
A	0043021	molecular_function	ribonucleoprotein complex binding
A	0043025	cellular_component	neuronal cell body
A	0045727	biological_process	positive regulation of translation
A	0048701	biological_process	embryonic cranial skeleton morphogenesis
A	0051028	biological_process	mRNA transport
A	0071006	cellular_component	U2-type catalytic step 1 spliceosome
A	0071013	cellular_component	catalytic step 2 spliceosome
A	0072715	biological_process	cellular response to selenite ion
A	0090394	biological_process	negative regulation of excitatory postsynaptic potential
A	0098794	cellular_component	postsynapse
A	0098978	cellular_component	glutamatergic synapse
A	0099578	biological_process	regulation of translation at postsynapse, modulating synaptic transmission
A	1904570	biological_process	negative regulation of selenocysteine incorporation
A	1990416	biological_process	cellular response to brain-derived neurotrophic factor stimulus
A	1990904	cellular_component	ribonucleoprotein complex
A	2000622	biological_process	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
B	0000184	biological_process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
B	0000381	biological_process	regulation of alternative mRNA splicing, via spliceosome
B	0000398	biological_process	mRNA splicing, via spliceosome
B	0003723	molecular_function	RNA binding
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0005681	cellular_component	spliceosomal complex
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006397	biological_process	mRNA processing
B	0006406	biological_process	mRNA export from nucleus
B	0006417	biological_process	regulation of translation
B	0008380	biological_process	RNA splicing
B	0016071	biological_process	mRNA metabolic process
B	0016607	cellular_component	nuclear speck
B	0035145	cellular_component	exon-exon junction complex
B	0050684	biological_process	regulation of mRNA processing
B	0051028	biological_process	mRNA transport
B	0071013	cellular_component	catalytic step 2 spliceosome
B	1990501	cellular_component	exon-exon junction subcomplex mago-y14
B	2000622	biological_process	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
C	0003676	molecular_function	nucleic acid binding
C	0003723	molecular_function	RNA binding
C	0003729	molecular_function	mRNA binding
C	0005634	cellular_component	nucleus
C	0005737	cellular_component	cytoplasm
C	0006396	biological_process	RNA processing
D	0003676	molecular_function	nucleic acid binding
D	0003723	molecular_function	RNA binding
D	0008643	biological_process	carbohydrate transport
D	0015144	molecular_function	carbohydrate transmembrane transporter activity
D	0055085	biological_process	transmembrane transport
F	0000166	molecular_function	nucleotide binding
F	0000184	biological_process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
F	0000398	biological_process	mRNA splicing, via spliceosome
F	0003676	molecular_function	nucleic acid binding
F	0003723	molecular_function	RNA binding
F	0003724	molecular_function	RNA helicase activity
F	0003729	molecular_function	mRNA binding
F	0004386	molecular_function	helicase activity
F	0005515	molecular_function	protein binding
F	0005524	molecular_function	ATP binding
F	0005634	cellular_component	nucleus
F	0005654	cellular_component	nucleoplasm
F	0005681	cellular_component	spliceosomal complex
F	0005730	cellular_component	nucleolus
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0006364	biological_process	rRNA processing
F	0006397	biological_process	mRNA processing
F	0006406	biological_process	mRNA export from nucleus
F	0006417	biological_process	regulation of translation
F	0008143	molecular_function	poly(A) binding
F	0008306	biological_process	associative learning
F	0008380	biological_process	RNA splicing
F	0010629	biological_process	negative regulation of gene expression
F	0016020	cellular_component	membrane
F	0016071	biological_process	mRNA metabolic process
F	0016607	cellular_component	nuclear speck
F	0016787	molecular_function	hydrolase activity
F	0016887	molecular_function	ATP hydrolysis activity
F	0017148	biological_process	negative regulation of translation
F	0030425	cellular_component	dendrite
F	0035145	cellular_component	exon-exon junction complex
F	0035368	molecular_function	selenocysteine insertion sequence binding
F	0035613	molecular_function	RNA stem-loop binding
F	0035640	biological_process	exploration behavior
F	0043021	molecular_function	ribonucleoprotein complex binding
F	0043025	cellular_component	neuronal cell body
F	0045727	biological_process	positive regulation of translation
F	0048701	biological_process	embryonic cranial skeleton morphogenesis
F	0051028	biological_process	mRNA transport
F	0071006	cellular_component	U2-type catalytic step 1 spliceosome
F	0071013	cellular_component	catalytic step 2 spliceosome
F	0072715	biological_process	cellular response to selenite ion
F	0090394	biological_process	negative regulation of excitatory postsynaptic potential
F	0098794	cellular_component	postsynapse
F	0098978	cellular_component	glutamatergic synapse
F	0099578	biological_process	regulation of translation at postsynapse, modulating synaptic transmission
F	1904570	biological_process	negative regulation of selenocysteine incorporation
F	1990416	biological_process	cellular response to brain-derived neurotrophic factor stimulus
F	1990904	cellular_component	ribonucleoprotein complex
F	2000622	biological_process	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
G	0000184	biological_process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
G	0000381	biological_process	regulation of alternative mRNA splicing, via spliceosome
G	0000398	biological_process	mRNA splicing, via spliceosome
G	0003723	molecular_function	RNA binding
G	0005515	molecular_function	protein binding
G	0005634	cellular_component	nucleus
G	0005654	cellular_component	nucleoplasm
G	0005681	cellular_component	spliceosomal complex
G	0005737	cellular_component	cytoplasm
G	0005829	cellular_component	cytosol
G	0006397	biological_process	mRNA processing
G	0006406	biological_process	mRNA export from nucleus
G	0006417	biological_process	regulation of translation
G	0008380	biological_process	RNA splicing
G	0016071	biological_process	mRNA metabolic process
G	0016607	cellular_component	nuclear speck
G	0035145	cellular_component	exon-exon junction complex
G	0050684	biological_process	regulation of mRNA processing
G	0051028	biological_process	mRNA transport
G	0071013	cellular_component	catalytic step 2 spliceosome
G	1990501	cellular_component	exon-exon junction subcomplex mago-y14
G	2000622	biological_process	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
H	0003676	molecular_function	nucleic acid binding
H	0003723	molecular_function	RNA binding
H	0003729	molecular_function	mRNA binding
H	0005634	cellular_component	nucleus
H	0005737	cellular_component	cytoplasm
H	0006396	biological_process	RNA processing
I	0003676	molecular_function	nucleic acid binding
I	0003723	molecular_function	RNA binding
I	0008643	biological_process	carbohydrate transport
I	0015144	molecular_function	carbohydrate transmembrane transporter activity
I	0055085	biological_process	transmembrane transport
K	0000166	molecular_function	nucleotide binding
K	0000184	biological_process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
K	0000398	biological_process	mRNA splicing, via spliceosome
K	0003676	molecular_function	nucleic acid binding
K	0003723	molecular_function	RNA binding
K	0003724	molecular_function	RNA helicase activity
K	0003729	molecular_function	mRNA binding
K	0004386	molecular_function	helicase activity
K	0005515	molecular_function	protein binding
K	0005524	molecular_function	ATP binding
K	0005634	cellular_component	nucleus
K	0005654	cellular_component	nucleoplasm
K	0005681	cellular_component	spliceosomal complex
K	0005730	cellular_component	nucleolus
K	0005737	cellular_component	cytoplasm
K	0005829	cellular_component	cytosol
K	0006364	biological_process	rRNA processing
K	0006397	biological_process	mRNA processing
K	0006406	biological_process	mRNA export from nucleus
K	0006417	biological_process	regulation of translation
K	0008143	molecular_function	poly(A) binding
K	0008306	biological_process	associative learning
K	0008380	biological_process	RNA splicing
K	0010629	biological_process	negative regulation of gene expression
K	0016020	cellular_component	membrane
K	0016071	biological_process	mRNA metabolic process
K	0016607	cellular_component	nuclear speck
K	0016787	molecular_function	hydrolase activity
K	0016887	molecular_function	ATP hydrolysis activity
K	0017148	biological_process	negative regulation of translation
K	0030425	cellular_component	dendrite
K	0035145	cellular_component	exon-exon junction complex
K	0035368	molecular_function	selenocysteine insertion sequence binding
K	0035613	molecular_function	RNA stem-loop binding
K	0035640	biological_process	exploration behavior
K	0043021	molecular_function	ribonucleoprotein complex binding
K	0043025	cellular_component	neuronal cell body
K	0045727	biological_process	positive regulation of translation
K	0048701	biological_process	embryonic cranial skeleton morphogenesis
K	0051028	biological_process	mRNA transport
K	0071006	cellular_component	U2-type catalytic step 1 spliceosome
K	0071013	cellular_component	catalytic step 2 spliceosome
K	0072715	biological_process	cellular response to selenite ion
K	0090394	biological_process	negative regulation of excitatory postsynaptic potential
K	0098794	cellular_component	postsynapse
K	0098978	cellular_component	glutamatergic synapse
K	0099578	biological_process	regulation of translation at postsynapse, modulating synaptic transmission
K	1904570	biological_process	negative regulation of selenocysteine incorporation
K	1990416	biological_process	cellular response to brain-derived neurotrophic factor stimulus
K	1990904	cellular_component	ribonucleoprotein complex
K	2000622	biological_process	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
L	0000184	biological_process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
L	0000381	biological_process	regulation of alternative mRNA splicing, via spliceosome
L	0000398	biological_process	mRNA splicing, via spliceosome
L	0003723	molecular_function	RNA binding
L	0005515	molecular_function	protein binding
L	0005634	cellular_component	nucleus
L	0005654	cellular_component	nucleoplasm
L	0005681	cellular_component	spliceosomal complex
L	0005737	cellular_component	cytoplasm
L	0005829	cellular_component	cytosol
L	0006397	biological_process	mRNA processing
L	0006406	biological_process	mRNA export from nucleus
L	0006417	biological_process	regulation of translation
L	0008380	biological_process	RNA splicing
L	0016071	biological_process	mRNA metabolic process
L	0016607	cellular_component	nuclear speck
L	0035145	cellular_component	exon-exon junction complex
L	0050684	biological_process	regulation of mRNA processing
L	0051028	biological_process	mRNA transport
L	0071013	cellular_component	catalytic step 2 spliceosome
L	1990501	cellular_component	exon-exon junction subcomplex mago-y14
L	2000622	biological_process	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
M	0003676	molecular_function	nucleic acid binding
M	0003723	molecular_function	RNA binding
M	0003729	molecular_function	mRNA binding
M	0005634	cellular_component	nucleus
M	0005737	cellular_component	cytoplasm
M	0006396	biological_process	RNA processing
N	0003676	molecular_function	nucleic acid binding
N	0003723	molecular_function	RNA binding
N	0008643	biological_process	carbohydrate transport
N	0015144	molecular_function	carbohydrate transmembrane transporter activity
N	0055085	biological_process	transmembrane transport
a	0000166	molecular_function	nucleotide binding
a	0000184	biological_process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
a	0000398	biological_process	mRNA splicing, via spliceosome
a	0003676	molecular_function	nucleic acid binding
a	0003723	molecular_function	RNA binding
a	0003724	molecular_function	RNA helicase activity
a	0003729	molecular_function	mRNA binding
a	0004386	molecular_function	helicase activity
a	0005515	molecular_function	protein binding
a	0005524	molecular_function	ATP binding
a	0005634	cellular_component	nucleus
a	0005654	cellular_component	nucleoplasm
a	0005681	cellular_component	spliceosomal complex
a	0005730	cellular_component	nucleolus
a	0005737	cellular_component	cytoplasm
a	0005829	cellular_component	cytosol
a	0006364	biological_process	rRNA processing
a	0006397	biological_process	mRNA processing
a	0006406	biological_process	mRNA export from nucleus
a	0006417	biological_process	regulation of translation
a	0008143	molecular_function	poly(A) binding
a	0008306	biological_process	associative learning
a	0008380	biological_process	RNA splicing
a	0010629	biological_process	negative regulation of gene expression
a	0016020	cellular_component	membrane
a	0016071	biological_process	mRNA metabolic process
a	0016607	cellular_component	nuclear speck
a	0016787	molecular_function	hydrolase activity
a	0016887	molecular_function	ATP hydrolysis activity
a	0017148	biological_process	negative regulation of translation
a	0030425	cellular_component	dendrite
a	0035145	cellular_component	exon-exon junction complex
a	0035368	molecular_function	selenocysteine insertion sequence binding
a	0035613	molecular_function	RNA stem-loop binding
a	0035640	biological_process	exploration behavior
a	0043021	molecular_function	ribonucleoprotein complex binding
a	0043025	cellular_component	neuronal cell body
a	0045727	biological_process	positive regulation of translation
a	0048701	biological_process	embryonic cranial skeleton morphogenesis
a	0051028	biological_process	mRNA transport
a	0071006	cellular_component	U2-type catalytic step 1 spliceosome
a	0071013	cellular_component	catalytic step 2 spliceosome
a	0072715	biological_process	cellular response to selenite ion
a	0090394	biological_process	negative regulation of excitatory postsynaptic potential
a	0098794	cellular_component	postsynapse
a	0098978	cellular_component	glutamatergic synapse
a	0099578	biological_process	regulation of translation at postsynapse, modulating synaptic transmission
a	1904570	biological_process	negative regulation of selenocysteine incorporation
a	1990416	biological_process	cellular response to brain-derived neurotrophic factor stimulus
a	1990904	cellular_component	ribonucleoprotein complex
a	2000622	biological_process	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
b	0000184	biological_process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
b	0000381	biological_process	regulation of alternative mRNA splicing, via spliceosome
b	0000398	biological_process	mRNA splicing, via spliceosome
b	0003723	molecular_function	RNA binding
b	0005515	molecular_function	protein binding
b	0005634	cellular_component	nucleus
b	0005654	cellular_component	nucleoplasm
b	0005681	cellular_component	spliceosomal complex
b	0005737	cellular_component	cytoplasm
b	0005829	cellular_component	cytosol
b	0006397	biological_process	mRNA processing
b	0006406	biological_process	mRNA export from nucleus
b	0006417	biological_process	regulation of translation
b	0008380	biological_process	RNA splicing
b	0016071	biological_process	mRNA metabolic process
b	0016607	cellular_component	nuclear speck
b	0035145	cellular_component	exon-exon junction complex
b	0050684	biological_process	regulation of mRNA processing
b	0051028	biological_process	mRNA transport
b	0071013	cellular_component	catalytic step 2 spliceosome
b	1990501	cellular_component	exon-exon junction subcomplex mago-y14
b	2000622	biological_process	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
c	0003676	molecular_function	nucleic acid binding
c	0003723	molecular_function	RNA binding
c	0003729	molecular_function	mRNA binding
c	0005634	cellular_component	nucleus
c	0005737	cellular_component	cytoplasm
c	0006396	biological_process	RNA processing
d	0003676	molecular_function	nucleic acid binding
d	0003723	molecular_function	RNA binding
d	0008643	biological_process	carbohydrate transport
d	0015144	molecular_function	carbohydrate transmembrane transporter activity
d	0055085	biological_process	transmembrane transport
f	0000166	molecular_function	nucleotide binding
f	0000184	biological_process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
f	0000398	biological_process	mRNA splicing, via spliceosome
f	0003676	molecular_function	nucleic acid binding
f	0003723	molecular_function	RNA binding
f	0003724	molecular_function	RNA helicase activity
f	0003729	molecular_function	mRNA binding
f	0004386	molecular_function	helicase activity
f	0005515	molecular_function	protein binding
f	0005524	molecular_function	ATP binding
f	0005634	cellular_component	nucleus
f	0005654	cellular_component	nucleoplasm
f	0005681	cellular_component	spliceosomal complex
f	0005730	cellular_component	nucleolus
f	0005737	cellular_component	cytoplasm
f	0005829	cellular_component	cytosol
f	0006364	biological_process	rRNA processing
f	0006397	biological_process	mRNA processing
f	0006406	biological_process	mRNA export from nucleus
f	0006417	biological_process	regulation of translation
f	0008143	molecular_function	poly(A) binding
f	0008306	biological_process	associative learning
f	0008380	biological_process	RNA splicing
f	0010629	biological_process	negative regulation of gene expression
f	0016020	cellular_component	membrane
f	0016071	biological_process	mRNA metabolic process
f	0016607	cellular_component	nuclear speck
f	0016787	molecular_function	hydrolase activity
f	0016887	molecular_function	ATP hydrolysis activity
f	0017148	biological_process	negative regulation of translation
f	0030425	cellular_component	dendrite
f	0035145	cellular_component	exon-exon junction complex
f	0035368	molecular_function	selenocysteine insertion sequence binding
f	0035613	molecular_function	RNA stem-loop binding
f	0035640	biological_process	exploration behavior
f	0043021	molecular_function	ribonucleoprotein complex binding
f	0043025	cellular_component	neuronal cell body
f	0045727	biological_process	positive regulation of translation
f	0048701	biological_process	embryonic cranial skeleton morphogenesis
f	0051028	biological_process	mRNA transport
f	0071006	cellular_component	U2-type catalytic step 1 spliceosome
f	0071013	cellular_component	catalytic step 2 spliceosome
f	0072715	biological_process	cellular response to selenite ion
f	0090394	biological_process	negative regulation of excitatory postsynaptic potential
f	0098794	cellular_component	postsynapse
f	0098978	cellular_component	glutamatergic synapse
f	0099578	biological_process	regulation of translation at postsynapse, modulating synaptic transmission
f	1904570	biological_process	negative regulation of selenocysteine incorporation
f	1990416	biological_process	cellular response to brain-derived neurotrophic factor stimulus
f	1990904	cellular_component	ribonucleoprotein complex
f	2000622	biological_process	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
g	0000184	biological_process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
g	0000381	biological_process	regulation of alternative mRNA splicing, via spliceosome
g	0000398	biological_process	mRNA splicing, via spliceosome
g	0003723	molecular_function	RNA binding
g	0005515	molecular_function	protein binding
g	0005634	cellular_component	nucleus
g	0005654	cellular_component	nucleoplasm
g	0005681	cellular_component	spliceosomal complex
g	0005737	cellular_component	cytoplasm
g	0005829	cellular_component	cytosol
g	0006397	biological_process	mRNA processing
g	0006406	biological_process	mRNA export from nucleus
g	0006417	biological_process	regulation of translation
g	0008380	biological_process	RNA splicing
g	0016071	biological_process	mRNA metabolic process
g	0016607	cellular_component	nuclear speck
g	0035145	cellular_component	exon-exon junction complex
g	0050684	biological_process	regulation of mRNA processing
g	0051028	biological_process	mRNA transport
g	0071013	cellular_component	catalytic step 2 spliceosome
g	1990501	cellular_component	exon-exon junction subcomplex mago-y14
g	2000622	biological_process	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
h	0003676	molecular_function	nucleic acid binding
h	0003723	molecular_function	RNA binding
h	0003729	molecular_function	mRNA binding
h	0005634	cellular_component	nucleus
h	0005737	cellular_component	cytoplasm
h	0006396	biological_process	RNA processing
i	0003676	molecular_function	nucleic acid binding
i	0003723	molecular_function	RNA binding
i	0008643	biological_process	carbohydrate transport
i	0015144	molecular_function	carbohydrate transmembrane transporter activity
i	0055085	biological_process	transmembrane transport
k	0000166	molecular_function	nucleotide binding
k	0000184	biological_process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
k	0000398	biological_process	mRNA splicing, via spliceosome
k	0003676	molecular_function	nucleic acid binding
k	0003723	molecular_function	RNA binding
k	0003724	molecular_function	RNA helicase activity
k	0003729	molecular_function	mRNA binding
k	0004386	molecular_function	helicase activity
k	0005515	molecular_function	protein binding
k	0005524	molecular_function	ATP binding
k	0005634	cellular_component	nucleus
k	0005654	cellular_component	nucleoplasm
k	0005681	cellular_component	spliceosomal complex
k	0005730	cellular_component	nucleolus
k	0005737	cellular_component	cytoplasm
k	0005829	cellular_component	cytosol
k	0006364	biological_process	rRNA processing
k	0006397	biological_process	mRNA processing
k	0006406	biological_process	mRNA export from nucleus
k	0006417	biological_process	regulation of translation
k	0008143	molecular_function	poly(A) binding
k	0008306	biological_process	associative learning
k	0008380	biological_process	RNA splicing
k	0010629	biological_process	negative regulation of gene expression
k	0016020	cellular_component	membrane
k	0016071	biological_process	mRNA metabolic process
k	0016607	cellular_component	nuclear speck
k	0016787	molecular_function	hydrolase activity
k	0016887	molecular_function	ATP hydrolysis activity
k	0017148	biological_process	negative regulation of translation
k	0030425	cellular_component	dendrite
k	0035145	cellular_component	exon-exon junction complex
k	0035368	molecular_function	selenocysteine insertion sequence binding
k	0035613	molecular_function	RNA stem-loop binding
k	0035640	biological_process	exploration behavior
k	0043021	molecular_function	ribonucleoprotein complex binding
k	0043025	cellular_component	neuronal cell body
k	0045727	biological_process	positive regulation of translation
k	0048701	biological_process	embryonic cranial skeleton morphogenesis
k	0051028	biological_process	mRNA transport
k	0071006	cellular_component	U2-type catalytic step 1 spliceosome
k	0071013	cellular_component	catalytic step 2 spliceosome
k	0072715	biological_process	cellular response to selenite ion
k	0090394	biological_process	negative regulation of excitatory postsynaptic potential
k	0098794	cellular_component	postsynapse
k	0098978	cellular_component	glutamatergic synapse
k	0099578	biological_process	regulation of translation at postsynapse, modulating synaptic transmission
k	1904570	biological_process	negative regulation of selenocysteine incorporation
k	1990416	biological_process	cellular response to brain-derived neurotrophic factor stimulus
k	1990904	cellular_component	ribonucleoprotein complex
k	2000622	biological_process	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
l	0000184	biological_process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
l	0000381	biological_process	regulation of alternative mRNA splicing, via spliceosome
l	0000398	biological_process	mRNA splicing, via spliceosome
l	0003723	molecular_function	RNA binding
l	0005515	molecular_function	protein binding
l	0005634	cellular_component	nucleus
l	0005654	cellular_component	nucleoplasm
l	0005681	cellular_component	spliceosomal complex
l	0005737	cellular_component	cytoplasm
l	0005829	cellular_component	cytosol
l	0006397	biological_process	mRNA processing
l	0006406	biological_process	mRNA export from nucleus
l	0006417	biological_process	regulation of translation
l	0008380	biological_process	RNA splicing
l	0016071	biological_process	mRNA metabolic process
l	0016607	cellular_component	nuclear speck
l	0035145	cellular_component	exon-exon junction complex
l	0050684	biological_process	regulation of mRNA processing
l	0051028	biological_process	mRNA transport
l	0071013	cellular_component	catalytic step 2 spliceosome
l	1990501	cellular_component	exon-exon junction subcomplex mago-y14
l	2000622	biological_process	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
m	0003676	molecular_function	nucleic acid binding
m	0003723	molecular_function	RNA binding
m	0003729	molecular_function	mRNA binding
m	0005634	cellular_component	nucleus
m	0005737	cellular_component	cytoplasm
m	0006396	biological_process	RNA processing
n	0003676	molecular_function	nucleic acid binding
n	0003723	molecular_function	RNA binding
n	0008643	biological_process	carbohydrate transport
n	0015144	molecular_function	carbohydrate transmembrane transporter activity
n	0055085	biological_process	transmembrane transport

Functional Information from PROSITE/UniProt

site_id	PS00039
Number of Residues	9
Details	DEAD_ATP_HELICASE DEAD-box subfamily ATP-dependent helicases signature. VLDEADEmL

Chain	Residue	Details
A	VAL185-LEU193

---

site_id	PS01037
Number of Residues	18
Details	SBP_BACTERIAL_1 Bacterial extracellular solute-binding proteins, family 1 signature. PIAvEalSLIYNkdlLpN

Chain	Residue	Details
n	PRO-220-ASN-203

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1020
Details	Domain: {"description":"Helicase ATP-binding","evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	168
Details	Motif: {"description":"Q motif"}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	18
Details	Motif: {"description":"DEAD box","evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	72
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16923391","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16931718","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19033377","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20479275","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2HYI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2J0Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2J0S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2XB2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3EX7","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	6
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"P60842","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	6
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	6
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"P60843","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	12
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	12
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"UniProtKB","id":"P60842","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	18
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	468
Details	Domain: {"description":"RRM","evidences":[{"source":"PROSITE-ProRule","id":"PRU00176","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	456
Details	Domain: {"description":"RRM","evidences":[{"source":"PubMed","id":"37020021","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	18
Details	Motif: {"description":"WXHD motif","evidences":[{"source":"PubMed","id":"37020021","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI14
Number of Residues	6
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"O08583","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI15
Number of Residues	6
Details	Modified residue: {"description":"Citrulline","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---