7ZDD
Crystal structure of TRIM33 PHD-Bromodomain isoform B in complex with H3K10ac histone peptide.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | E3 ubiquitin-protein ligase TRIM33 | polymer | 194 | 22274.5 | 1 | UniProt (Q9UPN9) Pfam (PF00628) Pfam (PF00439) | Homo sapiens (human) | Ectodermin homolog,RET-fused gene 7 protein,Protein Rfg7,Transcription intermediary factor 1-gamma,TIF1-gamma,Tripartite motif-containing protein 33 |
| 2 | B (D) | Histone H3.X | polymer | 10 | 1233.5 | 1 | UniProt (P0DPK5) | Homo sapiens | Histone H3.Y2 |
| 3 | C, D (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 4 | E, F, G (A, D) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
| 5 | H, I (A, D) | water | water | 18.0 | 182 | Chemie (HOH) |
Sequence modifications
A: 882 - 1073 (UniProt: Q9UPN9)
D: 1 - 10 (UniProt: P0DPK5)
| PDB | External Database | Details |
|---|---|---|
| Ser 880 | - | expression tag |
| Met 881 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Aly 10 | Ala 11 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 23507.9 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 320.4 | |
| All* | Total formula weight | 23828.3 |
