7Z78
Crystal structure of compound 4 in complex with the bromodomain of human SMARCA2 and pVHL:ElonginC:ElonginB
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C | Probable global transcription activator SNF2L2 | polymer | 123 | 14380.5 | 3 | UniProt (P51531) Pfam (PF00439) In PDB | Homo sapiens (human) | ATP-dependent helicase SMARCA2,BRG1-associated factor 190B,BAF190B,Protein brahma homolog,hBRM,SNF2-alpha,SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 |
| 2 | A, B, C | 4-bromanyl-7-cyclopentyl-9-piperidin-4-yl-benzimidazolo[1,2-a]quinazolin-5-one | non-polymer | 465.4 | 3 | Chemie (IF8) | |||
| 3 | A, B, C | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 4 | water | water | 18.0 | 427 | Chemie (HOH) |
Sequence modifications
A, B, C: 1373 - 1493 (UniProt: P51531)
| PDB | External Database | Details |
|---|---|---|
| Ser 1371 | - | expression tag |
| Met 1372 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 43141.6 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1657.8 | |
| All* | Total formula weight | 44799.4 |
