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7Z78

Crystal structure of compound 4 in complex with the bromodomain of human SMARCA2 and pVHL:ElonginC:ElonginB

Functional Information from GO Data
ChainGOidnamespacecontents
A0006338biological_processchromatin remodeling
A0016586cellular_componentRSC-type complex
B0006338biological_processchromatin remodeling
B0016586cellular_componentRSC-type complex
C0006338biological_processchromatin remodeling
C0016586cellular_componentRSC-type complex
Functional Information from PROSITE/UniProt
site_idPS00633
Number of Residues58
DetailsBROMODOMAIN_1 Bromodomain signature. SevFiqlpSrkelp..EYYelIrkpVdfkkIkerirnhk..Yrslgdlekdvml.LchNAqtF
ChainResidueDetails
ASER1406-PHE1463

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues3
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569
ChainResidueDetails
ASER1377
BSER1377
CSER1377

223532

PDB entries from 2024-08-07

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