7Z1K
Crystal structure of the SPOC domain of human SHARP (SPEN) in complex with RNA polymerase II CTD heptapeptide phosphorylated on Ser5
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Msx2-interacting protein | polymer | 172 | 18730.7 | 1 | UniProt (Q96T58) Pfam (PF07744) | Homo sapiens (human) | SMART/HDAC1-associated repressor protein,SPEN homolog |
| 2 | B (B) | SER-TYR-SER-PRO-THR-SEP | polymer | 16 | 1721.7 | 1 | Pfam (PF05001) UniProt (by SIFTS) (P24928) | Homo sapiens | |
| 3 | C, D (A, B) | water | water | 18.0 | 169 | Chemie (HOH) |
Sequence modifications
A: 3496 - 3664 (UniProt: Q96T58)
| PDB | External Database | Details |
|---|---|---|
| Gly 3493 | - | expression tag |
| Ala 3494 | - | expression tag |
| Met 3495 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 20452.4 | |
| All* | Total formula weight | 20452.4 |
