7YQE

Structure of human SRC regulatory domains in complex with the C-terminal PRRP motifs of GPR54.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Proto-oncogene tyrosine-protein kinase Src,KiSS-1 receptor	polymer	188	21404.9	2	UniProt (P12931) UniProt (Q969F8) Pfam (PF00018) Pfam (PF00017)	Homo sapiens (human)	Proto-oncogene c-Src,pp60c-src,p60-Src,KiSS-1R,G-protein coupled receptor 54,G-protein coupled receptor OT7T175,hOT7T175,Hypogonadotropin-1,Kisspeptins receptor,Metastin receptor

Sequence modifications

A, B: 85 - 247 (UniProt: P12931)
A, B: 333 - 357 (UniProt: Q969F8)

PDB	External Database	Details
Ser 338	Cys 338	engineered mutation
Ser 340	Cys 340	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	42809.8
All*	Total formula weight	42809.8

*Water molecules are not included.