7Y38
Molecular architecture of the chikungunya virus replication complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E... | mRNA-capping enzyme nsP1,affinity-tag (strepII-3XFLAG) | polymer | 573 | 64328.9 | 12 | UniProt (Q8JUX6) Pfam (PF01660) In PDB | Chikungunya virus strain S27-African prototype | Non-structural protein 1 |
2 | X | RNA-directed RNA polymerase nsP4 | polymer | 611 | 68373.3 | 1 | Pfam (PF00978) UniProt (by SIFTS) (O90368) In PDB | Onyong-nyong virus | |
3 | Y | Protease nsP2 | polymer | 798 | 89599.8 | 1 | UniProt (Q8JUX6) Pfam (PF20896) Pfam (PF01443) Pfam (PF01707) In PDB | Chikungunya virus strain S27-African prototype | Non-structural protein 2,nsP2 |
4 | Z | RNA (5'-R(P*CP*CP*A)-3') | polymer | 3 | 894.6 | 1 | in vitro transcription vector pT7-TP(deltai) | ||
5 | E, F, G, H, I... | ZINC ION | non-polymer | 65.4 | 12 | Chemie (ZN) | |||
6 | D, E, F, G, H... | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 12 | Chemie (ATP) | |||
7 | E, F, G, H, I... | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 12 | Chemie (GTP) |
Sequence modifications
A, B, C, D, E, F, G, H, I, J, K, L: 1 - 516 (UniProt: Q8JUX6)
A, B, C, D, E, F, G, H, I, J, K, L: 517 - 552 (PDB: 7Y38)
A, B, C, D, E, F, G, H, I, J, K, L: 553 - 570 (UniProt: Q8JUX6)
PDB | External Database | Details |
---|---|---|
Ala 37 | His 37 | engineered mutation |
A, B, C, D, E, F, G, H, I, J, K, L: 553 - 570 (UniProt: Q8JUX6)
PDB | External Database | Details |
---|---|---|
Asn 571 | - | expression tag |
Gly 572 | - | expression tag |
Leu 573 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 15 |
Total formula weight | 930815.0 | |
Non-Polymers* | Number of molecules | 36 |
Total formula weight | 13149.2 | |
All* | Total formula weight | 943964.2 |