7Y38

Molecular architecture of the chikungunya virus replication complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003723	molecular_function	RNA binding
A	0006396	biological_process	RNA processing
A	0008174	molecular_function	mRNA methyltransferase activity
A	0016556	biological_process	mRNA modification
B	0003723	molecular_function	RNA binding
B	0006396	biological_process	RNA processing
B	0008174	molecular_function	mRNA methyltransferase activity
B	0016556	biological_process	mRNA modification
C	0003723	molecular_function	RNA binding
C	0006396	biological_process	RNA processing
C	0008174	molecular_function	mRNA methyltransferase activity
C	0016556	biological_process	mRNA modification
D	0003723	molecular_function	RNA binding
D	0006396	biological_process	RNA processing
D	0008174	molecular_function	mRNA methyltransferase activity
D	0016556	biological_process	mRNA modification
E	0003723	molecular_function	RNA binding
E	0006396	biological_process	RNA processing
E	0008174	molecular_function	mRNA methyltransferase activity
E	0016556	biological_process	mRNA modification
F	0003723	molecular_function	RNA binding
F	0006396	biological_process	RNA processing
F	0008174	molecular_function	mRNA methyltransferase activity
F	0016556	biological_process	mRNA modification
G	0003723	molecular_function	RNA binding
G	0006396	biological_process	RNA processing
G	0008174	molecular_function	mRNA methyltransferase activity
G	0016556	biological_process	mRNA modification
H	0003723	molecular_function	RNA binding
H	0006396	biological_process	RNA processing
H	0008174	molecular_function	mRNA methyltransferase activity
H	0016556	biological_process	mRNA modification
I	0003723	molecular_function	RNA binding
I	0006396	biological_process	RNA processing
I	0008174	molecular_function	mRNA methyltransferase activity
I	0016556	biological_process	mRNA modification
J	0003723	molecular_function	RNA binding
J	0006396	biological_process	RNA processing
J	0008174	molecular_function	mRNA methyltransferase activity
J	0016556	biological_process	mRNA modification
K	0003723	molecular_function	RNA binding
K	0006396	biological_process	RNA processing
K	0008174	molecular_function	mRNA methyltransferase activity
K	0016556	biological_process	mRNA modification
L	0003723	molecular_function	RNA binding
L	0006396	biological_process	RNA processing
L	0008174	molecular_function	mRNA methyltransferase activity
L	0016556	biological_process	mRNA modification
X	0003723	molecular_function	RNA binding
X	0003968	molecular_function	RNA-directed RNA polymerase activity
X	0006351	biological_process	DNA-templated transcription
X	0039694	biological_process	viral RNA genome replication
Y	0005524	molecular_function	ATP binding

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2772
Details	Domain: {"description":"Alphavirus-like MT","evidences":[{"source":"PROSITE-ProRule","id":"PRU01079","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	12
Details	Active site: {"description":"For mRNA-capping enzyme nsP1 activity","evidences":[{"source":"PubMed","id":"33730549","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	48
Details	Binding site: {"evidences":[{"source":"PubMed","id":"33730549","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	12
Details	Site: {"description":"Involved in the phosphoramide link with 7-methyl-GMP","evidences":[{"source":"UniProtKB","id":"P27282","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	7
Details	Lipidation: {"description":"S-palmitoyl cysteine; by host","evidences":[{"source":"PubMed","id":"30404808","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	115
Details	Domain: {"description":"RdRp catalytic","evidences":[{"source":"PROSITE-ProRule","id":"PRU00539","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	152
Details	Domain: {"description":"(+)RNA virus helicase ATP-binding","evidences":[{"source":"PROSITE-ProRule","id":"PRU00990","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	148
Details	Domain: {"description":"(+)RNA virus helicase C-terminal","evidences":[{"source":"PROSITE-ProRule","id":"PRU00990","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	7
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00990","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---