7Y1G
Crystal structure of human PRKACA complexed with DS01080522
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | cAMP-dependent protein kinase catalytic subunit alpha | polymer | 351 | 40808.6 | 2 | UniProt (P17612) Pfam (PF00069) | Homo sapiens (human) | PKA C-alpha |
| 2 | C, D (A, B) | 1-chloranyl-~{N}-[(~{S})-(3-chloranyl-4-cyano-phenyl)-[(2~{R},4~{S})-4-oxidanylpyrrolidin-2-yl]methyl]-7-methoxy-isoquinoline-6-carboxamide | non-polymer | 471.3 | 2 | Chemie (I5G) | |||
| 3 | E (B) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | F, G (A, B) | water | water | 18.0 | 255 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 81617.1 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1008.1 | |
| All* | Total formula weight | 82625.2 |
