7XZ2

TRIM E3 ubiquitin ligase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	Tripartite motif-containing protein 72	polymer	466	51800.3	4	UniProt (Q1XH17) Pfam (PF13445) Pfam (PF00643) Pfam (PF13765) Pfam (PF00622) In PDB	Mus musculus (house mouse)	Mitsugumin-53,Mg53
2	A, B, C, D	ZINC ION	non-polymer		65.4	10	Chemie (ZN)

Sequence modifications

A, B, C, D: 7 - 470 (UniProt: Q1XH17)

PDB	External Database	Details
Gly 5	-	expression tag
Ser 6	-	expression tag
Ser 55	Cys 55	engineered mutation
Ser 144	Cys 144	engineered mutation
Ser 242	Cys 242	engineered mutation
His 279	Lys 279	engineered mutation
His 283	Ala 283	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	207201.2
Non-Polymers*	Number of molecules	10
	Total formula weight	654.1
All*	Total formula weight	207855.3

*Water molecules are not included.