7XUZ

Crystal structure of a HDAC4-MEF2A-DNA ternary complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, F (B, A)	Histone deacetylase 4	polymer	133	16081.4	2	UniProt (P56524) Pfam (PF12203)	Homo sapiens (human)	HD4
2	B, C, G, H (C, D, G, H)	myocyte-specific enhancer factor 2A isoform X4	polymer	97	11395.2	4	UniProt (A0A6J2KXN9) Pfam (PF00319) UniProt (by SIFTS) (Q02078)	Homo sapiens (human)
3	D, I (E, I)	DNA (5'-D(P*AP*CP*TP*AP*TP*TP*TP*AP*TP*AP*A)-3')	polymer	15	4600.0	2		Homo sapiens
4	E, J (F, J)	DNA (5'-D(*TP*CP*TP*TP*AP*TP*AP*AP*AP*TP*AP*GP*T)-3')	polymer	15	4573.0	2		Homo sapiens

Sequence modifications

B, A: 62 - 192 (UniProt: P56524)

PDB	External Database	Details
Gly 60	-	expression tag
Pro 61	-	expression tag

C, D, G, H: 1 - 95 (UniProt: A0A6J2KXN9)

PDB	External Database	Details
Gly -1	-	expression tag
Pro 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	10
	Total formula weight	96089.7
All*	Total formula weight	96089.7

*Water molecules are not included.