7XPY
Crystal structure of USP7 in complex with its inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Ubiquitin carboxyl-terminal hydrolase 7 | polymer | 548 | 64106.0 | 1 | UniProt (Q93009) Pfam (PF12436) Pfam (PF14533) | Homo sapiens (human) | Deubiquitinating enzyme 7,Herpesvirus-associated ubiquitin-specific protease,Ubiquitin thioesterase 7,Ubiquitin-specific-processing protease 7 |
| 2 | B (A) | [(3S,3aR,4R,6Z,9S,10E,11aR)-9-acetyloxy-6-(acetyloxymethyl)-3,10-dimethyl-2-oxidanylidene-3a,4,5,8,9,11a-hexahydro-3H-cyclodeca[b]furan-4-yl] (E)-2-methyl-4-oxidanyl-but-2-enoate | non-polymer | 464.5 | 1 | Chemie (EIB) | |||
| 3 | C (A) | water | water | 18.0 | 29 | Chemie (HOH) |
Sequence modifications
A: 560 - 1102 (UniProt: Q93009)
| PDB | External Database | Details |
|---|---|---|
| Gly 555 | - | expression tag |
| Pro 556 | - | expression tag |
| Leu 557 | - | expression tag |
| Gly 558 | - | expression tag |
| Ser 559 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 64106.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 464.5 | |
| All* | Total formula weight | 64570.5 |
