7X8X
structural insights into Mycobacterium tuberculosis ClpP1P2 inhibition by Cediranib: implications for developing antimicrobial agents targeting Clp protease
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, E, F, I... (A, O, C, Q, F...) | ATP-dependent Clp protease proteolytic subunit 2 | polymer | 197 | 21706.7 | 14 | UniProt (P9WPC2) Pfam (PF00574) UniProt (by SIFTS) (P9WPC3) | Mycobacterium tuberculosis CDC1551 | Endopeptidase Clp 2 |
| 2 | AA, BA, C, D, G... (B, P, D, R, I...) | ATP-dependent Clp protease proteolytic subunit 1 | polymer | 177 | 19296.0 | 14 | UniProt (P9WPC4) Pfam (PF00574) UniProt (by SIFTS) (P9WPC5) | Mycobacterium tuberculosis | Endopeptidase Clp 1 |
| 3 | AB, BB, CA, CB, DA... (c, e, f, g, h...) | 4-[[3,5-bis(fluoranyl)phenyl]methyl]-N-[(4-bromophenyl)methyl]piperazine-1-carboxamide | polymer | 3 | 348.4 | 28 | synthetic construct | ||
| 4 | EB, FB, GB, HB, IB... (B, R, F, I, U...) | 4-[1-[3-[4-[(4-fluoranyl-2-methyl-1H-indol-5-yl)oxy]-6-methoxy-quinazolin-7-yl]oxypropyl]piperidin-4-yl]benzamide | non-polymer | 583.7 | 14 | Chemie (AI4) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 56 |
| Total formula weight | 583795.1 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 8171.1 | |
| All* | Total formula weight | 591966.2 |
