7WZS

Crystal structure of Chromobacterium violaceum effector CopC in complex with host calmodulin and caspase-7

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	CopC	polymer	443	48446.5	1	UniProt (Q7NWF2) Pfam (PF06128) Pfam (PF13606)	Chromobacterium violaceum ATCC 12472
2	B (B)	Caspase-7	polymer	289	33055.7	1	UniProt (P55210) Pfam (PF00656)	Homo sapiens (human)	CASP-7
3	C (C)	Calmodulin-1	polymer	153	17251.0	1	UniProt (P0DP23) Pfam (PF13499)	Homo sapiens (human)

Sequence modifications

A: 51 - 487 (UniProt: Q7NWF2)

PDB	External Database	Details
Leu 45	-	expression tag
Gly 46	-	expression tag
Ser 47	-	expression tag
Gly 48	-	expression tag
Arg 49	-	expression tag
Pro 50	-	expression tag

B: 24 - 303 (UniProt: P55210)

PDB	External Database	Details
Met 23	-	initiating methionine
Ala 186	Cys 186	engineered mutation
Leu 304	-	expression tag
Glu 305	-	expression tag
His 306	-	expression tag
His 307	-	expression tag
His 308	-	expression tag
His 309	-	expression tag
His 310	-	expression tag
His 311	-	expression tag

C: 1 - 149 (UniProt: P0DP23)

PDB	External Database	Details
Ser -3	-	expression tag
Gly -2	-	expression tag
Arg -1	-	expression tag
Pro 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	98753.1
All*	Total formula weight	98753.1

*Water molecules are not included.