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7WTD

Cryo-EM structure of human pyruvate carboxylase with acetyl-CoA in the intermediate state 1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Pyruvate carboxylase, mitochondrialpolymer1178129799.44UniProt (P11498)
Pfam (PF00289)
Pfam (PF02786)
Pfam (PF02785)
Pfam (PF00682)
Pfam (PF02436)
Pfam (PF00364)
Homo sapiens (human)Pyruvic carboxylase,PCB
2E, H
(C, D)
ADENOSINE-5'-TRIPHOSPHATEnon-polymer507.22Chemie (ATP)
3F, G
(C, D)
COENZYME Anon-polymer767.52Chemie (COA)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight519197.4
Non-Polymers*Number of molecules4
Total formula weight2549.4
All*Total formula weight521746.9
*Water molecules are not included.

247947

PDB entries from 2026-01-21

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