7WMT
Crystal structure of small molecule 13 bound to human Nicotinamide N-methyltransferase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Nicotinamide N-methyltransferase | polymer | 250 | 27683.8 | 1 | UniProt (P40261) Pfam (PF01234) | Homo sapiens (human) | |
| 2 | B (A) | [(2~{R},4~{S})-4-[2-(aminomethyl)imidazol-1-yl]-2-[1-[(4-chlorophenyl)methyl]-5-methyl-indol-2-yl]pyrrolidin-1-yl]-(1~{H}-pyrrolo[2,3-b]pyridin-5-yl)methanone | non-polymer | 564.1 | 1 | Chemie (1IV) | |||
| 3 | C (A) | water | water | 18.0 | 202 | Chemie (HOH) |
Sequence modifications
A: 3 - 200 (UniProt: P40261)
A: 217 - 264 (UniProt: P40261)
| PDB | External Database | Details |
|---|---|---|
| Gly 2 | - | expression tag |
| Ala 103 | Glu 103 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Gly 214 | - | linker |
| Gly 215 | - | linker |
| Gly 216 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 27683.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 564.1 | |
| All* | Total formula weight | 28247.9 |
