7WMT
Crystal structure of small molecule 13 bound to human Nicotinamide N-methyltransferase
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008168 | molecular_function | methyltransferase activity |
Functional Information from PROSITE/UniProt
| site_id | PS01100 |
| Number of Residues | 17 |
| Details | NNMT_PNMT_TEMT NNMT/PNMT/TEMT family of methyltransferases signature. LIDIGSGPTIYQLLSAC |
| Chain | Residue | Details |
| A | LEU59-CYS75 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:21823666, ECO:0000269|Ref.12 |
| Chain | Residue | Details |
| A | TYR20 | |
| A | TYR25 | |
| A | GLY63 | |
| A | TYR69 | |
| A | ASP85 | |
| A | ASN90 | |
| A | ASP142 | |
| A | THR163 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:21823666 |
| Chain | Residue | Details |
| A | ASP197 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | MOD_RES: Citrulline; alternate => ECO:0000269|PubMed:30044909 |
| Chain | Residue | Details |
| A | ARG18 | |
| A | ARG132 | |
| A | ARG181 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861 |
| Chain | Residue | Details |
| A | LYS39 |
