7VKE
Crystal structure of human CD38 ECD in complex with UniDab(TM) F11A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | polymer | 264 | 30754.8 | 1 | UniProt (P28907) Pfam (PF02267) | Homo sapiens (Human) | 2'-phospho-ADP-ribosyl cyclase,2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase,2'-phospho-cyclic-ADP-ribose transferase,ADP-ribosyl cyclase 1,ADPRC 1,Cyclic ADP-ribose hydrolase 1,cADPr hydrolase 1,T10 |
| 2 | B (B) | Unidab F11A | polymer | 130 | 14586.3 | 1 | Homo sapiens | ||
| 3 | C, D, H (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 4 | E (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 5 | F (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 6 | G (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 7 | I, J (A, B) | water | water | 18.0 | 316 | Chemie (HOH) |
Sequence modifications
A: 45 - 300 (UniProt: P28907)
| PDB | External Database | Details |
|---|---|---|
| Thr 49 | Gln 49 | conflict |
| Asp 100 | Asn 100 | conflict |
| Ala 164 | Asn 164 | conflict |
| Asp 209 | Asn 209 | conflict |
| Asp 219 | Asn 219 | conflict |
| His 301 | - | expression tag |
| His 302 | - | expression tag |
| His 303 | - | expression tag |
| His 304 | - | expression tag |
| His 305 | - | expression tag |
| His 306 | - | expression tag |
| His 307 | - | expression tag |
| His 308 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 45341.1 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 269.0 | |
| All* | Total formula weight | 45610.0 |
