7VKE

Crystal structure of human CD38 ECD in complex with UniDab(TM) F11A

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1	polymer	264	30754.8	1	UniProt (P28907) Pfam (PF02267) In PDB	Homo sapiens (Human)	2'-phospho-ADP-ribosyl cyclase,2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase,2'-phospho-cyclic-ADP-ribose transferase,ADP-ribosyl cyclase 1,ADPRC 1,Cyclic ADP-ribose hydrolase 1,cADPr hydrolase 1,T10
2	B	Unidab F11A	polymer	130	14586.3	1		Homo sapiens
3	A, B	1,2-ETHANEDIOL	non-polymer		62.1	3	Chemie (EDO)
4	A	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
5	A	SODIUM ION	non-polymer		23.0	1	Chemie (NA)
6	A	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
7		water	water		18.0	316	Chemie (HOH)

Sequence modifications

A: 45 - 300 (UniProt: P28907)

PDB	External Database	Details
Thr 49	Gln 49	conflict
Asp 100	Asn 100	conflict
Ala 164	Asn 164	conflict
Asp 209	Asn 209	conflict
Asp 219	Asn 219	conflict
His 301	-	expression tag
His 302	-	expression tag
His 303	-	expression tag
His 304	-	expression tag
His 305	-	expression tag
His 306	-	expression tag
His 307	-	expression tag
His 308	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	45341.1
Non-Polymers*	Number of molecules	6
	Total formula weight	269.0
All*	Total formula weight	45610.0

*Water molecules are not included.