7USC
Cryo-EM structure of WAVE Regulatory Complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Cytoplasmic FMR1-interacting protein 1 | polymer | 1253 | 145363.8 | 1 | UniProt (Q7L576) Pfam (PF07159) Pfam (PF05994) In PDB | Homo sapiens (human) | Specifically Rac1-associated protein 1,Sra-1,p140sra-1 |
| 2 | B | Nck-associated protein 1 | polymer | 1128 | 128940.7 | 1 | UniProt (Q9Y2A7) Pfam (PF09735) In PDB | Homo sapiens (human) | NAP 1,Membrane-associated protein HEM-2,p125Nap1 |
| 3 | C | Wiskott-Aldrich syndrome protein family member 1 | polymer | 323 | 37009.4 | 1 | UniProt (Q92558) Pfam (PF02205) In PDB | Homo sapiens (human) | WASP family protein member 1,Protein WAVE-1,Verprolin homology domain-containing protein 1 |
| 4 | D | Protein BRICK1 | polymer | 75 | 8756.9 | 1 | UniProt (Q8WUW1) In PDB | Homo sapiens (human) | BRK1 |
| 5 | E | Abl interactor 2 | polymer | 158 | 18041.5 | 1 | UniProt (E9PEZ7) Pfam (PF07815) UniProt (by SIFTS) (Q9NYB9) In PDB | Homo sapiens (human) |
Sequence modifications
C: 1 - 466 (UniProt: Q92558)
C: 485 - 559 (UniProt: Q92558)
C: 485 - 559 (UniProt: Q92558)
| PDB | External Database | Details |
|---|---|---|
| Gly 467 | - | linker |
| Gly 468 | - | linker |
| Ser 469 | - | linker |
| Gly 470 | - | linker |
| Gly 471 | - | linker |
| Ser 472 | - | linker |
| Gly 473 | - | linker |
| Gly 474 | - | linker |
| Ser 475 | - | linker |
| Gly 476 | - | linker |
| Gly 477 | - | linker |
| Ser 478 | - | linker |
| Gly 479 | - | linker |
| Gly 480 | - | linker |
| Ser 481 | - | linker |
| Gly 482 | - | linker |
| Gly 483 | - | linker |
| Ser 484 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 338112.3 | |
| All* | Total formula weight | 338112.3 |
