7UAI
Meprin alpha helix in complex with fetuin-B
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | E, B, C, D | Meprin A subunit alpha | polymer | 587 | 67285.8 | 4 | UniProt (Q16819) Pfam (PF01400) Pfam (PF00629) Pfam (PF22486) In PDB | Homo sapiens (human) | Endopeptidase-2,N-benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha,PABA peptide hydrolase,PPH alpha |
| 2 | A, H | Fetuin-B | polymer | 388 | 42926.7 | 2 | UniProt (Q9UGM5) Pfam (PF00031) In PDB | Homo sapiens (human) | 16G2,Fetuin-like protein IRL685,Gugu |
| 3 | F, L, R | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 627.6 | 3 | In PDB GlyTouCan (G47362BJ) | |||
| 4 | G, J, K, M, O... | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 8 | In PDB GlyTouCan (G42666HT) | |||
| 5 | I, N, Q, T | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 732.7 | 4 | In PDB GlyTouCan (G32152BH) | |||
| 6 | B, C, D, E | CALCIUM ION | non-polymer | 40.1 | 8 | Chemie (CA) | |||
| 7 | B, C, E, A | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 8 | B, C, D, E | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) |
Sequence modifications
E, B, C, D: 22 - 600 (UniProt: Q16819)
A, H: 1 - 382 (UniProt: Q9UGM5)
| PDB | External Database | Details |
|---|---|---|
| Trp 14 | - | expression tag |
| Ser 15 | - | expression tag |
| His 16 | - | expression tag |
| Pro 17 | - | expression tag |
| Gln 18 | - | expression tag |
| Phe 19 | - | expression tag |
| Glu 20 | - | expression tag |
| Lys 21 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| His 383 | - | expression tag |
| His 384 | - | expression tag |
| His 385 | - | expression tag |
| His 386 | - | expression tag |
| His 387 | - | expression tag |
| His 388 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 354996.7 | |
| Branched | Number of molecules | 15 |
| Total formula weight | 8208.7 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 1467.1 | |
| All* | Total formula weight | 364672.5 |
