7U0L
Crystal structure of the CCoV-HuPn-2018 RBD (domain B) in complex with canine APN
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Aminopeptidase N | polymer | 908 | 103563.3 | 1 | UniProt (P79143) Pfam (PF17900) Pfam (PF01433) Pfam (PF11838) In PDB | Canis lupus familiaris (dog) | AP-N,cAPN,Alanyl aminopeptidase,Aminopeptidase M,AP-M,Microsomal aminopeptidase |
| 2 | B | Spike glycoprotein | polymer | 182 | 20211.4 | 1 | UniProt (A0A8E6CMP0) Pfam (PF01600) In PDB | Coronaviridae sp. | S glycoprotein,E2,Peplomer protein |
| 3 | C | alpha-D-mannopyranose-(1-3)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB | |||
| 4 | D, L | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 2 | In PDB GlyTouCan (G22768VO) | |||
| 5 | E | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1057.0 | 1 | In PDB GlyTouCan (G82348BZ) | |||
| 6 | F, I | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 2 | In PDB GlyTouCan (G15407YE) | |||
| 7 | G, K | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 8 | H | alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1073.0 | 1 | In PDB GlyTouCan (G00850LT) | |||
| 9 | J, M | alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 894.8 | 2 | In PDB GlyTouCan (G00395TQ) | |||
| 10 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 11 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 12 | water | water | 18.0 | 65 | Chemie (HOH) |
Sequence modifications
A: 72 - 973 (UniProt: P79143)
B: 523 - 682 (UniProt: A0A8E6CMP0)
| PDB | External Database | Details |
|---|---|---|
| Thr 71 | - | expression tag |
| Gly 974 | - | expression tag |
| Gly 975 | - | expression tag |
| Ser 976 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Thr 522 | - | expression tag |
| Gly 672 | - | insertion |
| Ser 673 | - | insertion |
| Ser 674 | - | insertion |
| Gly 675 | - | insertion |
| Gly 676 | - | insertion |
| Asn 680 | His 675 | conflict |
| Ile 682 | Leu 677 | conflict |
| Phe 683 | - | expression tag |
| Glu 684 | - | expression tag |
| Ala 685 | - | expression tag |
| Gln 686 | - | expression tag |
| Lys 687 | - | expression tag |
| Ile 688 | - | expression tag |
| Glu 689 | - | expression tag |
| Trp 690 | - | expression tag |
| His 691 | - | expression tag |
| Glu 692 | - | expression tag |
| Gly 693 | - | expression tag |
| Gly 694 | - | expression tag |
| Ser 695 | - | expression tag |
| His 696 | - | expression tag |
| His 697 | - | expression tag |
| His 698 | - | expression tag |
| His 699 | - | expression tag |
| His 700 | - | expression tag |
| His 701 | - | expression tag |
| His 702 | - | expression tag |
| His 703 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 123774.6 | |
| Branched | Number of molecules | 11 |
| Total formula weight | 8511.8 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 507.8 | |
| All* | Total formula weight | 132794.2 |
