7U0L

Crystal structure of the CCoV-HuPn-2018 RBD (domain B) in complex with canine APN

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001525	biological_process	angiogenesis
A	0001618	molecular_function	virus receptor activity
A	0004177	molecular_function	aminopeptidase activity
A	0005615	cellular_component	extracellular space
A	0005737	cellular_component	cytoplasm
A	0005886	cellular_component	plasma membrane
A	0006508	biological_process	proteolysis
A	0008237	molecular_function	metallopeptidase activity
A	0008270	molecular_function	zinc ion binding
A	0030154	biological_process	cell differentiation
A	0042277	molecular_function	peptide binding
A	0043171	biological_process	peptide catabolic process
A	0046718	biological_process	symbiont entry into host cell
A	0046872	molecular_function	metal ion binding
A	0070006	molecular_function	metalloaminopeptidase activity
B	0019064	biological_process	fusion of virus membrane with host plasma membrane

Functional Information from PROSITE/UniProt

site_id	PS00142
Number of Residues	10
Details	ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. VIAHELAHQW

Chain	Residue	Details
A	VAL391-TRP400

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton acceptor => ECO:0000255|PROSITE-ProRule:PRU10095

Chain	Residue	Details
A	GLU395

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site_id	SWS_FT_FI2
Number of Residues	2
Details	BINDING: BINDING => ECO:0000250|UniProtKB:P15144

Chain	Residue	Details
A	GLY358
A	GLU417

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site_id	SWS_FT_FI3
Number of Residues	2
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU10095

Chain	Residue	Details
A	HIS394
A	HIS398

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site_id	SWS_FT_FI4
Number of Residues	1
Details	SITE: Transition state stabilizer => ECO:0000250|UniProtKB:P15144

Chain	Residue	Details
A	TYR483

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site_id	SWS_FT_FI5
Number of Residues	3
Details	MOD_RES: Sulfotyrosine => ECO:0000255

Chain	Residue	Details
A	TYR182
A	TYR425
A	TYR430

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site_id	SWS_FT_FI6
Number of Residues	8
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000250|UniProtKB:P15144

Chain	Residue	Details
A	ASN134
A	ASN240
A	ASN271
A	ASN533
A	ASN580
A	ASN633
A	ASN689
A	ASN826

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site_id	SWS_FT_FI7
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255

Chain	Residue	Details
A	ASN747

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