7TZG

Structure of human LAG3 in complex with antibody single-chain variable fragment

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	scFvF7	polymer	248	25802.6	2		Homo sapiens (human)
2	C, D	Lymphocyte activation gene 3 protein	polymer	408	44344.2	2	UniProt (P18627) In PDB	Homo sapiens (human)	LAG-3
3	C, D	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	7	Chemie (NAG)

Sequence modifications

C, D: 23 - 430 (UniProt: P18627)

PDB	External Database	Details
Ile 171	Met 171	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	140293.7
Non-Polymers*	Number of molecules	7
	Total formula weight	1548.5
All*	Total formula weight	141842.1

*Water molecules are not included.