7TZG
Structure of human LAG3 in complex with antibody single-chain variable fragment
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | scFvF7 | polymer | 248 | 25802.6 | 2 | Homo sapiens (human) | ||
| 2 | C, D (C, D) | Lymphocyte activation gene 3 protein | polymer | 408 | 44344.2 | 2 | UniProt (P18627) | Homo sapiens (human) | LAG-3 |
| 3 | E, F, G, H, I... (C, D) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 7 | Chemie (NAG) |
Sequence modifications
C, D: 23 - 430 (UniProt: P18627)
| PDB | External Database | Details |
|---|---|---|
| Ile 171 | Met 171 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 140293.7 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1548.5 | |
| All* | Total formula weight | 141842.1 |
