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7TXT

Structure of human serotonin transporter bound to small molecule '8090 in lipid nanodisc and NaCl

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(C)
15B8 Fab heavy chainpolymer12013166.71Mus musculus
2B
(D)
15B8 Fab light chainpolymer11111905.21Mus musculus
3C
(S)
Sodium-dependent serotonin transporterpolymer54161062.11UniProt (P31645)
Pfam (PF00209)
Homo sapiens (human)SERT,5HT transporter,5HTT,Solute carrier family 6 member 4
4D
(S)
1-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]piperazinenon-polymer263.31Chemie (KWC)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight86134.1
Non-Polymers*Number of molecules1
Total formula weight263.3
All*Total formula weight86397.5
*Water molecules are not included.

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PDB entries from 2026-01-14

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