7THO

Integrin alpha IIB beta3 complex with Eptifibatide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	Integrin alpha-IIb	polymer	454	49228.6	2	UniProt (P08514) Pfam (PF01839)	Homo sapiens (human)	GPalpha IIb,GPIIb,Platelet membrane glycoprotein IIb
2	B, D (B, D)	Integrin beta-3	polymer	471	51958.8	2	UniProt (P05106) Pfam (PF17205) Pfam (PF00362) Pfam (PF18372)	Homo sapiens (human)	Platelet membrane glycoprotein IIIa,GPIIIa
3	E, G (E, H)	Fab heavy chain	polymer	216	23339.1	2		Mus musculus (mouse)
4	F, H (F, L)	Fab light chain	polymer	214	23332.7	2		Mus musculus (mouse)
5	I, J (M, N)	Eptifibatide	polymer	8	833.0	2	BIRD (PRD_002490)	synthetic construct
6	K (G)	beta-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		748.7	1	In PDB GlyTouCan (G31886NL)
7	L, N (I, K)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	2	In PDB GlyTouCan (G42666HT)
8	M (J)	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	1	In PDB GlyTouCan (G15407YE)
9	AA, EA, FA, O, P... (C, D, A, B)	CALCIUM ION	non-polymer		40.1	12	Chemie (CA)
10	BA, CA, HA, S (C, L, A)	SULFATE ION	non-polymer		96.1	4	Chemie (SO4)
11	DA, T (D, B)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
12	GA, W (D, B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
13	IA, JA, KA, LA, MA... (A, B, C, D, E...)	water	water		18.0	404	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	10
	Total formula weight	297384.3
Branched	Number of molecules	4
	Total formula weight	2184.0
Non-Polymers*	Number of molecules	20
	Total formula weight	1356.2
All*	Total formula weight	300924.5

*Water molecules are not included.