7SXJ
BIO-2895 (BRD0705) bound GSK3beta-axin complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Glycogen synthase kinase-3 beta | polymer | 351 | 39883.7 | 1 | UniProt (P49841) Pfam (PF00069) | Homo sapiens (Human) | GSK-3 beta,Serine/threonine-protein kinase GSK3B |
| 2 | B (B) | axin peptide | polymer | 17 | 2040.3 | 1 | UniProt (by SIFTS) (O15169) | Homo sapiens | |
| 3 | C (A) | (4~{S})-4-ethyl-7,7-dimethyl-4-phenyl-2,6,8,9-tetrahydropyrazolo[3,4-b]quinolin-5-one | non-polymer | 321.4 | 1 | Chemie (6VL) | |||
| 4 | D, E (A, B) | water | water | 18.0 | 213 | Chemie (HOH) |
Sequence modifications
A: 34 - 383 (UniProt: P49841)
| PDB | External Database | Details |
|---|---|---|
| Gly 33 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 41924.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 321.4 | |
| All* | Total formula weight | 42245.4 |
