7ST8

Crystal structure of 7H2.2 Fab in complex with SAS1B C-terminal region

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (H)	7H2.2 Fab Heavy Chain	polymer	223	23838.8	1		Mus musculus
2	B (L)	7H2.2 Fab Light Chain	polymer	217	23852.4	1		Mus musculus
3	C (S)	Astacin-like metalloendopeptidase	polymer	170	17209.0	1	UniProt (Q6HA08)	Homo sapiens (human)	SAS1B, Oocyte astacin,Ovastacin,ZP2-proteinase
4	D, E, F (H, L, S)	water	water		18.0	26	Chemie (HOH)

Sequence modifications

S: 284 - 431 (UniProt: Q6HA08)

PDB	External Database	Details
Met 262	-	initiating methionine
Gly 263	-	expression tag
Ser 264	-	expression tag
Ser 265	-	expression tag
His 266	-	expression tag
His 267	-	expression tag
His 268	-	expression tag
His 269	-	expression tag
His 270	-	expression tag
His 271	-	expression tag
Ser 272	-	expression tag
Ser 273	-	expression tag
Gly 274	-	expression tag
Leu 275	-	expression tag
Val 276	-	expression tag
Pro 277	-	expression tag
Arg 278	-	expression tag
Gly 279	-	expression tag
Ser 280	-	expression tag
His 281	-	expression tag
Met 282	-	expression tag
Ala 283	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	64900.1
All*	Total formula weight	64900.1

*Water molecules are not included.