7ST3
Consequences of HLA single chain trimer mutations on peptide presentation and binding affinity
This is a non-PDB format compatible entry.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C, E, G, I... | Protein E7 peptide,Beta-2-microglobulin,MHC class I antigen chimera | polymer | 429 | 48279.1 | 16 | UniProt (P03129) UniProt (P16213) UniProt (A0A678ZGP6) Pfam (PF07654) Pfam (PF00129) In PDB | Human papillomavirus type 16 | |
2 | B, D, F, H, J... | VHH | polymer | 116 | 12536.8 | 16 | Lama glama | ||
3 | water | water | 18.0 | 198 | Chemie (HOH) |
Sequence modifications
A, C, E, G, I, K, M, O, Q, S, U, W, Y, a, c, e: 1 - 5 (UniProt: P03129)
A, C, E, G, I, K, M, O, Q, S, U, W, Y, a, c, e: 25 - 123 (UniProt: P16213)
A, C, E, G, I, K, M, O, Q, S, U, W, Y, a, c, e: 144 - 418 (UniProt: A0A678ZGP6)
PDB | External Database | Details |
---|---|---|
Gly 5 | - | linker |
Gly 5 | - | linker |
Gly 5 | - | linker |
Gly 5 | - | linker |
Ser 5 | - | linker |
Gly 5 | - | linker |
Gly 5 | - | linker |
Gly 5 | - | linker |
Gly 5 | - | linker |
Ser 5 | - | linker |
Gly 5 | - | linker |
Gly 5 | - | linker |
Gly 5 | - | linker |
Gly 5 | - | linker |
Ser 5 | - | linker |
PDB | External Database | Details |
---|---|---|
Gly 124 | - | linker |
Gly 125 | - | linker |
Gly 126 | - | linker |
Gly 127 | - | linker |
Ser 128 | - | linker |
Gly 129 | - | linker |
Gly 130 | - | linker |
Gly 131 | - | linker |
Gly 132 | - | linker |
Ser 133 | - | linker |
Gly 134 | - | linker |
Gly 135 | - | linker |
Gly 136 | - | linker |
Gly 137 | - | linker |
Ser 138 | - | linker |
Gly 139 | - | linker |
Gly 140 | - | linker |
Gly 141 | - | linker |
Gly 142 | - | linker |
Ser 143 | - | linker |
PDB | External Database | Details |
---|---|---|
Cys 227 | Tyr 108 | engineered mutation |
Cys 282 | Ala 163 | engineered mutation |
His 419 | - | expression tag |
His 420 | - | expression tag |
His 421 | - | expression tag |
His 422 | - | expression tag |
His 423 | - | expression tag |
His 424 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 32 |
Total formula weight | 973054.3 | |
All* | Total formula weight | 973054.3 |