7ST3

Consequences of HLA single chain trimer mutations on peptide presentation and binding affinity

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0002474	biological_process	antigen processing and presentation of peptide antigen via MHC class I
A	0005576	cellular_component	extracellular region
A	0006955	biological_process	immune response
A	0042612	cellular_component	MHC class I protein complex
C	0002474	biological_process	antigen processing and presentation of peptide antigen via MHC class I
C	0005576	cellular_component	extracellular region
C	0006955	biological_process	immune response
C	0042612	cellular_component	MHC class I protein complex
E	0002474	biological_process	antigen processing and presentation of peptide antigen via MHC class I
E	0005576	cellular_component	extracellular region
E	0006955	biological_process	immune response
E	0042612	cellular_component	MHC class I protein complex
G	0002474	biological_process	antigen processing and presentation of peptide antigen via MHC class I
G	0005576	cellular_component	extracellular region
G	0006955	biological_process	immune response
G	0042612	cellular_component	MHC class I protein complex
I	0002474	biological_process	antigen processing and presentation of peptide antigen via MHC class I
I	0005576	cellular_component	extracellular region
I	0006955	biological_process	immune response
I	0042612	cellular_component	MHC class I protein complex
K	0002474	biological_process	antigen processing and presentation of peptide antigen via MHC class I
K	0005576	cellular_component	extracellular region
K	0006955	biological_process	immune response
K	0042612	cellular_component	MHC class I protein complex
M	0002474	biological_process	antigen processing and presentation of peptide antigen via MHC class I
M	0005576	cellular_component	extracellular region
M	0006955	biological_process	immune response
M	0042612	cellular_component	MHC class I protein complex
O	0002474	biological_process	antigen processing and presentation of peptide antigen via MHC class I
O	0005576	cellular_component	extracellular region
O	0006955	biological_process	immune response
O	0042612	cellular_component	MHC class I protein complex
Q	0002474	biological_process	antigen processing and presentation of peptide antigen via MHC class I
Q	0005576	cellular_component	extracellular region
Q	0006955	biological_process	immune response
Q	0042612	cellular_component	MHC class I protein complex
S	0002474	biological_process	antigen processing and presentation of peptide antigen via MHC class I
S	0005576	cellular_component	extracellular region
S	0006955	biological_process	immune response
S	0042612	cellular_component	MHC class I protein complex
U	0002474	biological_process	antigen processing and presentation of peptide antigen via MHC class I
U	0005576	cellular_component	extracellular region
U	0006955	biological_process	immune response
U	0042612	cellular_component	MHC class I protein complex
W	0002474	biological_process	antigen processing and presentation of peptide antigen via MHC class I
W	0005576	cellular_component	extracellular region
W	0006955	biological_process	immune response
W	0042612	cellular_component	MHC class I protein complex
Y	0002474	biological_process	antigen processing and presentation of peptide antigen via MHC class I
Y	0005576	cellular_component	extracellular region
Y	0006955	biological_process	immune response
Y	0042612	cellular_component	MHC class I protein complex
a	0002474	biological_process	antigen processing and presentation of peptide antigen via MHC class I
a	0005576	cellular_component	extracellular region
a	0006955	biological_process	immune response
a	0042612	cellular_component	MHC class I protein complex
c	0002474	biological_process	antigen processing and presentation of peptide antigen via MHC class I
c	0005576	cellular_component	extracellular region
c	0006955	biological_process	immune response
c	0042612	cellular_component	MHC class I protein complex
e	0002474	biological_process	antigen processing and presentation of peptide antigen via MHC class I
e	0005576	cellular_component	extracellular region
e	0006955	biological_process	immune response
e	0042612	cellular_component	MHC class I protein complex

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACRVNH

Chain	Residue	Details
A	TYR102-HIS108
A	TYR400-HIS406

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