7SQL
Crystal structure of human uridine-cytidine kinase 2 complexed with a weak small molecule inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Uridine-cytidine kinase 2 | polymer | 250 | 28108.8 | 4 | UniProt (Q9BZX2) Pfam (PF00485) | Homo sapiens (Human) | UCK 2,Cytidine monophosphokinase 2,Testis-specific protein TSA903,Uridine monophosphokinase 2 |
| 2 | E, F (A) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 2 | Chemie (PGE) | |||
| 3 | G, J, M, P (A, B, C, D) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 4 | H, O (B, D) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 2 | Chemie (PG4) | |||
| 5 | I, L, Q (B, C, D) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 3 | Chemie (PEG) | |||
| 6 | K, N (C, D) | N-(4-bromophenyl)-2-{[1-(4-fluorophenyl)-4-oxo-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-6-yl]sulfanyl}acetamide | non-polymer | 474.3 | 2 | Chemie (AQX) | |||
| 7 | R, S, T, U (A, B, C, D) | water | water | 18.0 | 233 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 112435.3 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 2324.1 | |
| All* | Total formula weight | 114759.5 |
