7SMS

Cryo-EM structure of Torpedo acetylcholine receptor in complex with d-tubocurarine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D	Acetylcholine receptor subunit alpha	polymer	437	50168.2	2	UniProt (P02710) Pfam (PF02931) Pfam (PF02932) In PDB	Tetronarce californica (Pacific electric ray)
2	B	Acetylcholine receptor subunit delta	polymer	501	57625.7	1	UniProt (P02718) Pfam (PF02931) Pfam (PF02932) In PDB	Tetronarce californica (Pacific electric ray)
3	C	Acetylcholine receptor subunit beta	polymer	469	53731.8	1	UniProt (P02712) Pfam (PF02931) Pfam (PF02932) In PDB	Tetronarce californica (Pacific electric ray)
4	E	Acetylcholine receptor subunit gamma	polymer	489	56335.7	1	UniProt (P02714) Pfam (PF02931) Pfam (PF02932) In PDB	Tetronarce californica (Pacific electric ray Torpedo californica)
5	F, I, J	alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		910.8	3	In PDB GlyTouCan (G94626GC)
6	G	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
7	H	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	1	In PDB GlyTouCan (G15407YE)
8	A, C, D	CHOLESTEROL	non-polymer		386.7	3	Chemie (CLR)
9	B, D, E	D-TUBOCURARINE	non-polymer		610.7	4	Chemie (TC9)
10	B, C, D, E	(2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate	non-polymer		760.1	5	Chemie (POV)

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	268029.5
Branched	Number of molecules	5
	Total formula weight	3743.4
Non-Polymers*	Number of molecules	12
	Total formula weight	7403.3
All*	Total formula weight	279176.2

*Water molecules are not included.