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7S7J

Structure of Human SPASTIN-IST1 complex.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Spastinpolymer849779.31UniProt (Q9UBP0)Homo sapiens (Human)Spastic paraplegia 4 protein
2B
(B)
IST1 homologpolymer232736.01UniProt (P53990)Homo sapienshIST1,Putative MAPK-activating protein PM28
3C
(A)
TETRAETHYLENE GLYCOLnon-polymer194.21Chemie (PG4)
4D
(B)
CALCIUM IONnon-polymer40.11Chemie (CA)
5E
(B)
TRIETHYLENE GLYCOLnon-polymer150.21Chemie (PGE)
6F
(B)
CHLORIDE IONnon-polymer35.51Chemie (CL)
7G, H
(A, B)
waterwater18.0112Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight12515.3
Non-Polymers*Number of molecules4
Total formula weight419.9
All*Total formula weight12935.2
*Water molecules are not included.

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PDB entries from 2026-02-11

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