7RX9

Structure of autoinhibited P-Rex1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein, Endolysin chimera	polymer	606	70026.7	1	UniProt (Q8TCU6) UniProt (P00720) Pfam (PF00621) Pfam (PF22697) Pfam (PF00959) Pfam (PF00610)	Homo sapiens (Human)	P-Rex1,PtdIns(3,4,5)-dependent Rac exchanger 1,Lysis protein,Lysozyme,Muramidase,P-Rex1,PtdIns(3,4,5)-dependent Rac exchanger 1
2	B, C, D, E, F... (A)	SULFATE ION	non-polymer		96.1	6	Chemie (SO4)

Sequence modifications

A: 41 - 305 (UniProt: Q8TCU6)

PDB	External Database	Details
Gly 40	-	expression tag

A: 306 - 465 (UniProt: P00720)
A: 466 - 645 (UniProt: Q8TCU6)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	70026.7
Non-Polymers*	Number of molecules	6
	Total formula weight	576.4
All*	Total formula weight	70603.1

*Water molecules are not included.